Peptide serum: benefits, how to use & price comparison
Peptides are short chains of amino acids; some act as signals that, in lab studies, encourage collagen production; Reviews of cosmeceutical peptides report small improvements in the look of fine lines and firmness in some trials, but studies are often small and industry-funded.
Listed MRP per ml ranges from ₹9.36 to ₹53.30 across 5 products.
Price comparison
| Brand | Product | Key actives | Size | MRP | ₹ / ml | As on |
|---|---|---|---|---|---|---|
| The Derma Co | The Derma Co Snail Peptide 96 Hydrating Serum | Snail Mucin, Peptide Complex | 80 ml | ₹749.00 | ₹9.36 | 19 October 2026 |
| Minimalist | Minimalist Multi-Peptides 10% Face Serum | Multi-Peptides 10% | 30 ml | ₹699.00 | ₹23.30 | 19 October 2026 |
| Hyphen | Hyphen 10% Peptide with 2% Copper Peptide Face Serum | Peptide 10%, Copper Peptide 2% | 30 ml | ₹799.00 | ₹26.63 | 19 October 2026 |
| Dr. Sheth's | Dr. Sheth's Argireline Peptide & Copper Peptide B'tox Serum | Argireline peptide, Copper Peptide | 30 ml | ₹1499.00 | ₹49.97 | 19 October 2026 |
| The Derma Co | The Derma Co Skin Renew Hyperpigmentation Peptide Serum | Peptides | 30 ml | ₹1599.00 | ₹53.30 | 19 October 2026 |
These are cosmetics. A cosmetic cannot treat or prevent a skin, scalp or hair condition. Product names and claims are the brands' own; Medyzen has not tested these products. MRPs are as listed on the date shown and may have changed. Listing is by price per ml/g, not a recommendation.
What it does
- Peptides are short chains of amino acids; some act as signals that, in lab studies, encourage collagen production.
- Reviews of cosmeceutical peptides report small improvements in the look of fine lines and firmness in some trials, but studies are often small and industry-funded.
- Copper peptides and acetyl hexapeptide-8 (Argireline) are popular examples; how well they penetrate skin varies by formula.
- Peptides are generally gentle, so they are an option for people who cannot tolerate retinol.
How to use
Apply 2 to 3 drops to clean skin once or twice a day, before moisturiser. Use sunscreen every morning. Give it at least 8 to 12 weeks. Patch-test behind your ear or on your inner arm for 7 to 10 days first.
Can be combined with / Avoid combining with
Can be combined with
- Hyaluronic acid
- Niacinamide
- Retinol (on alternate nights or in a separate layer)
- Sunscreen
Avoid combining with
- Copper peptides in the same application as strong acids or vitamin C (use at different times)
- Too many new actives at once
Possible side effects
- Mild redness or itching
- Stinging on broken skin
- Breakouts in some people
Who should avoid it
- Anyone allergic to an ingredient in the product
- Broken or irritated skin
- If you are pregnant or breastfeeding, data are limited; check with your doctor
Frequently asked questions
What does a peptide serum do?
It may help the look of fine lines and firmness over months, based on small studies. It is not a substitute for sunscreen, which has stronger evidence against photoageing.
Peptide serum vs retinol: which is better for wrinkles?
Retinoids have more evidence. Peptides are gentler and can be used by people who cannot tolerate retinol, or alongside it.
Can I use peptide serum with retinol?
Yes. Use them in separate layers or on alternate nights if your skin is sensitive.
Can I use copper peptides with vitamin C?
It is often advised to use them at different times of day, for example vitamin C in the morning and copper peptides at night.
At what age should I start a peptide serum?
There is no fixed age. Many people start in their late 20s or 30s, but sunscreen matters more at any age.
Minimalist multi-peptide serum side effects
It is usually well tolerated, but some people get mild redness, itching or breakouts. Patch-test first.
Is peptide serum safe for sensitive skin?
Peptides are generally gentle, but fragrance or other ingredients can irritate. Patch-test first.
Peptide serum morning or night?
Either. Most people use it at night and sunscreen in the morning.
Sources
- PubMed: Cosmeceutical peptides (19 October 2026)
- PubMed: Acetyl Hexapeptide-8 in Cosmeceuticals-A Review of Skin Permeability and Efficacy (19 October 2026)
- PubMed: Cosmeceuticals for antiaging: a systematic review of safety and efficacy (19 October 2026)
- American Academy of Dermatology: How to test skin care products (19 October 2026)
Medyzen Editorial Team · Last updated
This page is general cosmetic information, not medical advice. A cosmetic cannot treat a skin condition; see a doctor or dermatologist for acne, pigmentation or any persistent skin problem. Terms