Amaryl 1 vs Amaryl M 1: price, salt & differences
Amaryl 1 is glimepiride 1 mg alone, which makes the pancreas release more insulin. Amaryl M 1 adds metformin 500 mg (slow release), which cuts the liver's sugar output and improves insulin sensitivity – so one tablet covers two mechanisms, the usual pairing in type 2 diabetes. Amaryl 1 is ₹119.07 for 30 tablets and Amaryl M 1 is ₹302.97 for 20 tablets; both carry a low-sugar risk from glimepiride, so ask your doctor or pharmacist before switching.
Amaryl M 1
Glimepiride + Metformin 1 mg + 500 mg (SR) · Sanofi India Ltd
MRP ₹302.97 for 20
₹15.15 / tablet
Glimepiride + Metformin 1 mg + 500 mg (SR) detailsKey differences
| Aspect | Amaryl 1 | Amaryl M 1 |
|---|---|---|
| Salt / composition | Glimepiride | Glimepiride + Metformin |
| Strength | 1 mg | 1 mg + 500 mg (SR) |
| Manufacturer | Sanofi India Ltd | Sanofi India Ltd |
| Pack size | 30 tablets | 20 tablets |
| MRP | ₹119.07 for 30 tablets | ₹302.97 for 20 tablets |
| ₹ per tablet | ₹3.97 per tablet | ₹15.15 per tablet |
| Prescription status | Schedule H – prescription required | Schedule H – prescription required |
| Main use | Type 2 diabetes – lowers blood sugar by helping the pancreas release more insulin. | Type 2 diabetes when diet, exercise and metformin alone are not enough. |
| Who it suits / key caution | Type 2 diabetes when metformin alone is not enough. Can cause low blood sugar – never skip meals after taking it; elderly need extra care. | Type 2 diabetes needing both drugs, in one tablet with breakfast. Low sugar risk from the glimepiride part – do not skip meals; check kidneys for the metformin part. |
MRPs as printed/listed on the date shown; actual price may vary.
Frequently asked questions
Amaryl 1 और Amaryl M 1 में क्या अंतर है?
Amaryl 1 में सिर्फ glimepiride 1 mg है। Amaryl M 1 में glimepiride 1 mg के साथ metformin 500 mg भी है, जो sugar control के लिए दो तरह से काम करता है। कीमत: Amaryl 1 ₹119.07 (30 tablets), Amaryl M 1 ₹302.97 (20 tablets)।
Who takes Amaryl 1 alone?
People who cannot take metformin – for example with very weak kidneys or bad stomach intolerance – or whose doctor is adding glimepiride on top of a separate metformin tablet.
Who takes Amaryl M 1?
People with type 2 diabetes who need both metformin and glimepiride and prefer one tablet with breakfast. It is the lowest-strength combination, often the first step up from metformin alone.
Does the metformin in Amaryl M 1 add side effects?
Metformin can cause nausea, loose stools and a metallic taste at first, and needs regular kidney checks. Taking it with food reduces the stomach effects.
Can I take Amaryl M 1 with Glycomet 500?
Only if your doctor has planned the total metformin dose. Both contain metformin, so unplanned combining can exceed the intended dose.
Which is cheaper?
Amaryl 1 at ₹3.97 per tablet versus Amaryl M 1 at ₹15.15 per tablet. Jan Aushadhi glimepiride 1 is ₹4.13 for 10 tablets (₹0.41 per tablet); glimepiride + metformin is ₹16.5 for 10 tablets (₹1.65 per tablet).
Sources
- MedlinePlus – Glimepiride (19 October 2026)
- NPPA Pharma Sahi Daam (ceiling prices) (19 October 2026)
- PMBI Jan Aushadhi Product & MRP List (19 October 2026)
- NHS – Metformin (19 October 2026)
Medyzen Editorial Team · Last updated
This page is general information, not medical advice. Do not start, stop or change a medicine without asking a doctor or pharmacist. Terms