Vildagliptin 50 mg: uses, price & cheaper substitutes
Prescription required (Schedule H)
Common uses: Type 2 diabetes – lowering blood sugar when diet and exercise are not enough; Added to metformin when metformin alone no longer controls sugar.
Listed MRPs range from ₹1.25 to ₹24.75 per tablet across 8 listings. Use only on a doctor's prescription.
Price comparison
| Brand | Manufacturer | Pack | MRP | ₹ / tablet | As on |
|---|---|---|---|---|---|
| Vildagliptin Tablets IP 50mgJan Aushadhi | Jan Aushadhi (PMBJP) | 15 | ₹18.75 | ₹1.25 | 19 October 2026 |
| Galvamark 50 | Glenmark Pharmaceuticals Ltd | 15 | ₹121.87 | ₹8.12 | 19 October 2026 |
| Vildamac 50 | Macleods Pharmaceuticals Pvt Ltd | 15 | ₹148.21 | ₹9.88 | 19 October 2026 |
| Vildapride 50 | Micro Labs Ltd | 15 | ₹191.20 | ₹12.75 | 19 October 2026 |
| Zomelis 50 | Eris Lifesciences Ltd | 15 | ₹203.62 | ₹13.57 | 19 October 2026 |
| Vysov 50 | Cipla Ltd | 15 | ₹203.80 | ₹13.59 | 19 October 2026 |
| Jalra 50 | USV Private Limited | 15 | ₹347.98 | ₹23.20 | 19 October 2026 |
| Galvus 50 | Novartis India Ltd | 15 | ₹371.25 | ₹24.75 | 19 October 2026 |
MRPs as printed/listed on the date shown; actual price may vary.
Uses
- Type 2 diabetes – lowering blood sugar when diet and exercise are not enough.
- Added to metformin when metformin alone no longer controls sugar.
- Combined with a sulphonylurea (glimepiride), pioglitazone or insulin, as your doctor decides.
- Used alone when metformin is not tolerated.
How to take it
The usual dose is 50 mg twice a day – one tablet in the morning and one in the evening – when taken alone or with metformin, pioglitazone or insulin. With a sulphonylurea like glimepiride, or if you have moderate to severe kidney disease, the dose is 50 mg once in the morning. The maximum is 100 mg a day. Swallow the tablet whole with water, with or without food. Your doctor will test your liver function before starting, every three months in the first year and then periodically. Keep following your diet and exercise plan – the tablet adds to them, it does not replace them.
Side effects
Common
- Sore throat, runny nose or fever (very common).
- Headache, dizziness or trembling.
- Itchy rash.
- Swollen hands, ankles or feet.
- Nausea, constipation, diarrhoea or heartburn.
Serious
Stop and get medical help urgently if you notice any of these.
- Liver problems – yellow eyes or skin, dark urine, loss of appetite, nausea. Stop and see your doctor at once.
- Pancreatitis – severe persistent stomach pain going through to the back, with vomiting.
- Angioedema – sudden swelling of the face, tongue or throat, breathing difficulty.
- New blisters or skin ulcers, particularly on the feet – report promptly.
Safety information
Alcohol
Limit alcohol. It raises the risk of low blood sugar when vildagliptin is combined with glimepiride or insulin, and it strains the liver, which this medicine can affect.
Pregnancy
Do not use in pregnancy or while breastfeeding. Tell your doctor if you are planning a pregnancy so your diabetes medicine can be changed.
Kidney problems
The dose is reduced to 50 mg once a day in moderate or severe kidney disease and on dialysis. Your doctor will check kidney function.
Liver problems
Not for people with liver disease or raised liver enzymes. Liver tests are done before and during treatment; stop and see your doctor if you notice yellowing of the eyes.
Children
Not recommended under 18.
Missed dose
Take it as soon as you remember, then the next dose at the usual time; if the next dose is nearly due, skip the missed one. Do not take a double dose.
Interactions
- Glimepiride, gliclazide and insulin – higher chance of low blood sugar; your doctor may lower their dose.
- Steroids (prednisolone), water pills (thiazides) and thyroid medicines – can raise blood sugar and need dose adjustment.
- Some medicines acting on the nervous system – tell your doctor.
- ACE inhibitors (ramipril, enalapril) – slightly higher risk of angioedema.
Frequently asked questions
Galvus 50 before or after food?
Either. Vildagliptin can be taken with or without food. Many people take it with breakfast and dinner so they do not forget.
Galvus 50 vs Galvus Met – what is the difference?
Galvus 50 contains only vildagliptin. Galvus Met combines vildagliptin 50 mg with metformin 500, 850 or 1000 mg in one tablet, for people who need both. Your doctor decides the combination.
Does vildagliptin cause low blood sugar?
On its own, rarely. Low sugar becomes more likely when it is combined with glimepiride, gliclazide or insulin, which is why the dose is reduced to once a day with a sulphonylurea. Carry something sugary and learn the warning signs.
Why does my doctor check liver tests on Jalra?
Vildagliptin can rarely inflame the liver. Liver enzymes are checked before starting, every three months in the first year and then periodically. Stop and see your doctor if you notice yellow eyes, dark urine or loss of appetite.
Can I take Galvus 50 with alcohol?
Keep alcohol to a minimum. It increases the risk of low blood sugar when combined with other diabetes medicines and adds strain to the liver.
Vildagliptin vs sitagliptin – which is better?
Both are DPP-4 inhibitors with similar sugar-lowering effect. Sitagliptin is taken once a day, vildagliptin usually twice, and vildagliptin needs liver monitoring. Price and your kidney and liver function usually decide the choice.
Does Galvus cause weight gain?
No. DPP-4 inhibitors like vildagliptin are weight-neutral, unlike sulphonylureas and insulin, which can cause weight gain.
Is Galvus safe in pregnancy?
No. Vildagliptin should not be used in pregnancy or while breastfeeding. Tell your doctor if you are planning a baby – insulin or metformin are used instead.
Is vildagliptin available at Jan Aushadhi?
Yes, generic vildagliptin 50 mg tablets are available at Jan Aushadhi kendras at a much lower price than branded versions. It is a Schedule H medicine, so carry a prescription.
Sources
- eMC – Galvus 50 mg (vildagliptin) patient leaflet (19 October 2026)
- NPPA Pharma Sahi Daam (ceiling prices) (19 October 2026)
- PMBI Jan Aushadhi Product & MRP List (19 October 2026)
Medyzen Editorial Team · Last updated
This page is general information, not medical advice. Do not start, stop or change a medicine without asking a doctor or pharmacist. Terms