Dolo 650 vs Brufen 400: price, salt & differences
Dolo 650 is paracetamol – it lowers fever and eases pain but does little for swelling, and is the gentler choice for the stomach, in pregnancy and for most people. Brufen 400 is ibuprofen, an anti-inflammatory that works better for pain with swelling (sprains, dental pain, period cramps) but must be taken after food and avoided with ulcers, weak kidneys or heart failure. Dolo 650 is ₹32.28 for 15 tablets and over the counter; Brufen 400 is ₹25.75 for 20 tablets and Schedule H – ask your doctor or pharmacist before switching.
Dolo 650
Paracetamol 650 mg · Micro Labs Ltd
MRP ₹32.28 for 15
₹2.15 / tablet
Paracetamol 650 mg detailsKey differences
| Aspect | Dolo 650 | Brufen 400 |
|---|---|---|
| Salt / composition | Paracetamol | Ibuprofen |
| Strength | 650 mg | 400 mg |
| Manufacturer | Micro Labs Ltd | Abbott |
| Pack size | 15 tablets | 20 tablets |
| MRP | ₹32.28 for 15 tablets | ₹25.75 for 20 tablets |
| ₹ per tablet | ₹2.15 per tablet | ₹1.29 per tablet |
| Prescription status | Over the counter (no prescription needed) | Schedule H – prescription required |
| Main use | Fever from viral infections, flu, dengue, chikungunya or after vaccination. | Headache and migraine. |
| Who it suits / key caution | Adults with fever or mild to moderate pain; the usual first choice in pregnancy. Keep to the daily limit and avoid heavy alcohol – overdose harms the liver. | Pain with swelling – sprains, dental pain, period pain. Take after food; avoid if you have a stomach ulcer, weak kidneys, heart failure or in late pregnancy. |
MRPs as printed/listed on the date shown; actual price may vary.
Frequently asked questions
Dolo 650 और Brufen 400 में क्या अंतर है?
Dolo 650 में paracetamol है – बुखार और दर्द के लिए, पेट के लिए हल्की। Brufen 400 में ibuprofen है – सूजन वाले दर्द में ज़्यादा असरदार, पर खाने के बाद लेनी होती है और पेट/किडनी पर असर कर सकती है। Dolo 650 ₹32.28 (15 tablets), Brufen 400 ₹25.75 (20 tablets)।
Which is better for fever – paracetamol or ibuprofen?
Both bring fever down. Paracetamol is the usual first choice because it is gentler on the stomach and safe for more people; ibuprofen is an option if paracetamol is not enough and your stomach and kidneys are healthy.
Which is better for a sprain or toothache?
Ibuprofen, because it reduces inflammation as well as pain. Paracetamol still helps with the pain itself and can be combined with ibuprofen on a doctor's advice.
Can I take Dolo 650 and Brufen 400 together?
Doctors sometimes alternate or combine them for short periods because they work differently. Do not do this on your own for more than a day or two, and never exceed either daily limit.
Which is safer in pregnancy?
Paracetamol. Ibuprofen is avoided in pregnancy, especially the last three months, because it can affect the baby's heart and kidneys.
Do I need a prescription?
Dolo 650 is over the counter. Brufen 400 is Schedule H in India and formally needs a prescription, though it is widely available; use it only after food and for a few days.
Sources
- NHS – Paracetamol for adults (19 October 2026)
- MedlinePlus – Acetaminophen (paracetamol) (19 October 2026)
- NPPA Pharma Sahi Daam (ceiling prices) (19 October 2026)
- PMBI Jan Aushadhi Product & MRP List (19 October 2026)
- NHS – Ibuprofen for adults (19 October 2026)
Medyzen Editorial Team · Last updated
This page is general information, not medical advice. Do not start, stop or change a medicine without asking a doctor or pharmacist. Terms