Glycomet 500 vs Amaryl 1: price, salt & differences
Glycomet 500 is metformin 500 mg, the first-line diabetes tablet – it reduces the sugar the liver makes, does not cause low blood sugar on its own and may help weight. Amaryl 1 is glimepiride 1 mg, a sulfonylurea that pushes the pancreas to release more insulin; it works faster but can cause low blood sugar and some weight gain, so it is usually added when metformin alone is not enough. Glycomet 500 is ₹19.59 for 10 tablets and Amaryl 1 is ₹119.07 for 30 tablets; ask your doctor or pharmacist before switching.
Glycomet 500
Metformin 500 mg · USV Private Limited
MRP ₹19.59 for 10
₹1.96 / tablet
Metformin 500 mg detailsKey differences
| Aspect | Glycomet 500 | Amaryl 1 |
|---|---|---|
| Salt / composition | Metformin | Glimepiride |
| Strength | 500 mg | 1 mg |
| Manufacturer | USV Private Limited | Sanofi India Ltd |
| Pack size | 10 tablets | 30 tablets |
| MRP | ₹19.59 for 10 tablets | ₹119.07 for 30 tablets |
| ₹ per tablet | ₹1.96 per tablet | ₹3.97 per tablet |
| Prescription status | Schedule H – prescription required | Schedule H – prescription required |
| Main use | Type 2 diabetes – the first-choice tablet to lower blood sugar, along with diet and exercise. | Type 2 diabetes – lowers blood sugar by helping the pancreas release more insulin. |
| Who it suits / key caution | First-line tablet for type 2 diabetes; also used in PCOS. Take with meals; stomach upset is common early on. Check kidney function regularly. | Type 2 diabetes when metformin alone is not enough. Can cause low blood sugar – never skip meals after taking it; elderly need extra care. |
MRPs as printed/listed on the date shown; actual price may vary.
Frequently asked questions
Glycomet 500 और Amaryl 1 में क्या अंतर है?
Glycomet 500 में metformin है – diabetes की पहली दवा, sugar कम (hypo) नहीं करती। Amaryl 1 में glimepiride है – insulin बढ़ाती है, जल्दी असर पर hypoglycaemia का खतरा। Glycomet 500 ₹19.59 (10 tablets), Amaryl 1 ₹119.07 (30 tablets)।
Which is the first medicine for type 2 diabetes?
Metformin, unless the kidneys are too weak or it is not tolerated. Glimepiride is a common second medicine added on.
Which causes low blood sugar?
Glimepiride (Amaryl 1) can, especially if you skip meals or exercise hard. Metformin alone almost never does.
Which affects weight?
Metformin is weight-neutral or helps slightly; glimepiride can cause modest weight gain.
Can I take Glycomet 500 and Amaryl 1 together?
Yes, this is a very common combination prescribed by doctors; it is also sold as one tablet (Glycomet-GP). The doctor sets both doses.
Which is cheaper?
Glycomet 500 at ₹1.96 per tablet versus Amaryl 1 at ₹3.97 per tablet. NPPA ceilings are ₹2.07 per 1 tablet and ₹3.78 per 1 tablet; Jan Aushadhi metformin 500 is ₹6.19 for 10 tablets (₹0.62 per tablet) and glimepiride 1 is ₹4.13 for 10 tablets (₹0.41 per tablet).
Sources
- NHS – Metformin (19 October 2026)
- MedlinePlus – Metformin (19 October 2026)
- NPPA Pharma Sahi Daam (ceiling prices) (19 October 2026)
- PMBI Jan Aushadhi Product & MRP List (19 October 2026)
- MedlinePlus – Glimepiride (19 October 2026)
Medyzen Editorial Team · Last updated
This page is general information, not medical advice. Do not start, stop or change a medicine without asking a doctor or pharmacist. Terms