Glycomet 500 vs Glycomet-GP 1: price, salt & differences
Glycomet 500 is metformin 500 mg, the usual first tablet for type 2 diabetes. Glycomet-GP 1 adds glimepiride 1 mg, a sulfonylurea that makes the pancreas release more insulin, in one slow-release tablet – prescribed when metformin alone no longer keeps sugar in range. The combination can cause low blood sugar, so meals must not be skipped; Glycomet 500 is ₹19.59 for 10 tablets and Glycomet-GP 1 is ₹123.28 for 15 tablets. Ask your doctor or pharmacist before switching.
Glycomet 500
Metformin 500 mg · USV Private Limited
MRP ₹19.59 for 10
₹1.96 / tablet
Metformin 500 mg detailsGlycomet-GP 1
Glimepiride + Metformin 1 mg + 500 mg (SR) · USV Private Limited
MRP ₹123.28 for 15
₹8.22 / tablet
Glimepiride + Metformin 1 mg + 500 mg (SR) detailsKey differences
| Aspect | Glycomet 500 | Glycomet-GP 1 |
|---|---|---|
| Salt / composition | Metformin | Glimepiride + Metformin |
| Strength | 500 mg | 1 mg + 500 mg (SR) |
| Manufacturer | USV Private Limited | USV Private Limited |
| Pack size | 10 tablets | 15 tablets |
| MRP | ₹19.59 for 10 tablets | ₹123.28 for 15 tablets |
| ₹ per tablet | ₹1.96 per tablet | ₹8.22 per tablet |
| Prescription status | Schedule H – prescription required | Schedule H – prescription required |
| Main use | Type 2 diabetes – the first-choice tablet to lower blood sugar, along with diet and exercise. | Type 2 diabetes when diet, exercise and metformin alone are not enough. |
| Who it suits / key caution | First-line tablet for type 2 diabetes; also used in PCOS. Take with meals; stomach upset is common early on. Check kidney function regularly. | Type 2 diabetes needing both drugs, in one tablet with breakfast. Low sugar risk from the glimepiride part – do not skip meals; check kidneys for the metformin part. |
MRPs as printed/listed on the date shown; actual price may vary.
Frequently asked questions
Glycomet 500 और Glycomet GP 1 में क्या अंतर है?
Glycomet 500 में सिर्फ metformin 500 mg है। Glycomet-GP 1 में metformin 500 mg के साथ glimepiride 1 mg भी है, जो insulin बढ़ाकर sugar और नीचे लाता है, पर इससे sugar कम (hypoglycaemia) हो सकती है। कीमत: Glycomet 500 ₹19.59 (10 tablets), Glycomet-GP 1 ₹123.28 (15 tablets)।
When does a doctor add glimepiride to metformin?
When HbA1c or fasting sugar stays above target despite a good metformin dose, diet and exercise. Glycomet-GP 1 is the lowest-strength combination, often the first step up.
Does Glycomet-GP 1 cause low blood sugar?
It can, because of glimepiride. Learn the signs – sweating, shaking, hunger, confusion – keep glucose handy and never skip the meal you take it with. Plain metformin rarely causes low sugar on its own.
Can I take Glycomet 500 and Glycomet-GP 1 together?
Only if your doctor plans the total metformin dose that way. Both contain metformin, so doubling up without advice can exceed the intended dose.
Which is better for PCOS?
Plain metformin (Glycomet 500) is what is used in PCOS. Glimepiride combinations are for type 2 diabetes, not PCOS.
Which is cheaper?
Glycomet 500 is ₹1.96 per tablet and Glycomet-GP 1 is ₹8.22 per tablet. Jan Aushadhi metformin 500 is ₹6.19 for 10 tablets (₹0.62 per tablet); the glimepiride + metformin generic is ₹16.5 for 10 tablets (₹1.65 per tablet).
Sources
- NHS – Metformin (19 October 2026)
- MedlinePlus – Metformin (19 October 2026)
- NPPA Pharma Sahi Daam (ceiling prices) (19 October 2026)
- PMBI Jan Aushadhi Product & MRP List (19 October 2026)
- MedlinePlus – Glimepiride (19 October 2026)
Medyzen Editorial Team · Last updated
This page is general information, not medical advice. Do not start, stop or change a medicine without asking a doctor or pharmacist. Terms