Pantoprazole 40 mg: uses, price & cheaper substitutes
Prescription required (Schedule H)
Common uses: Acid reflux (GERD) – heartburn, sour burps and acid coming up into the throat; Stomach and duodenal ulcers, including ulcers caused by painkillers (NSAIDs).
Listed MRPs range from ₹1.14 to ₹16.53 per tablet across 5 listings. Use only on a doctor's prescription.
Price comparison
| Brand | Manufacturer | Pack | MRP | ₹ / tablet | As on |
|---|---|---|---|---|---|
| Pantoprazole Gastro Resistant Tablets IP 40 mgJan Aushadhi | Jan Aushadhi (PMBJP) | 10 | ₹11.35 | ₹1.14 | 19 October 2026 |
| Pantop 40 | Aristo Pharmaceuticals Pvt Ltd | 15 | ₹174.45 | ₹11.63 | 19 October 2026 |
| Pan 40 | Alkem Laboratories Ltd | 15 | ₹192.80 | ₹12.85 | 19 October 2026 |
| Pantocid 40 | Sun Pharmaceutical Industries Ltd | 15 | ₹195.94 | ₹13.06 | 19 October 2026 |
| Pantodac 40 | Zydus Cadila | 15 | ₹247.96 | ₹16.53 | 19 October 2026 |
MRPs as printed/listed on the date shown; actual price may vary.
Uses
- Acid reflux (GERD) – heartburn, sour burps and acid coming up into the throat.
- Stomach and duodenal ulcers, including ulcers caused by painkillers (NSAIDs).
- Protecting the stomach while you take long-term painkillers or steroids.
- Helicobacter pylori infection, along with antibiotics.
- Zollinger-Ellison syndrome and other conditions where the stomach makes too much acid.
How to take it
Take one 40 mg tablet once a day, usually 30 to 60 minutes before breakfast. Swallow it whole with water; do not crush or chew because the coating protects the medicine from stomach acid. Your doctor may ask you to take it for 4 to 8 weeks for reflux or ulcers; do not keep taking it for months without a review.
Side effects
Common
- Headache.
- Diarrhoea or constipation.
- Nausea, stomach pain, bloating or gas.
- Dizziness.
Serious
Stop and get medical help urgently if you notice any of these.
- Severe watery diarrhoea that does not stop (possible gut infection) – see a doctor.
- Low magnesium after months of use – muscle cramps, irregular heartbeat, fits.
- Signs of a severe allergic or skin reaction – rash with blisters, swelling of the face, difficulty breathing.
- Long-term use is linked with a higher risk of fractures and vitamin B12 deficiency; your doctor should review whether you still need it.
Safety information
Alcohol
Alcohol does not react with pantoprazole directly, but it makes acidity and reflux worse, so limit it while you are being treated.
Pregnancy
Tell your doctor if you are pregnant or breastfeeding. Pantoprazole is used in pregnancy only if clearly needed; antacids may be tried first.
Kidney problems
No dose change is usually needed, but tell your doctor about kidney disease. Rarely PPIs can cause a kidney inflammation (interstitial nephritis).
Liver problems
If you have severe liver disease your doctor may use a lower dose or check your liver tests.
Children
Not routinely used in children under 12 unless a specialist prescribes it.
Missed dose
Take it as soon as you remember, unless your next dose is due soon – then skip the missed one. Do not take two tablets together.
Interactions
- Medicines that need stomach acid to be absorbed – ketoconazole, itraconazole, some HIV medicines (atazanavir) and iron tablets may work less well.
- Methotrexate – levels can rise with high doses.
- Warfarin – bleeding risk may change; INR may need checking.
- Clopidogrel – pantoprazole is thought to interact less than omeprazole, but tell your cardiologist.
- Other acid medicines (ranitidine, antacids) – usually no need to combine; ask your doctor.
Frequently asked questions
Pan 40 before or after food?
Before food. Take Pan 40 about 30 to 60 minutes before breakfast so the medicine is active when your stomach starts making acid for the meal.
Can I take Pan 40 daily for a long time?
Only if your doctor has reviewed you. Short courses of 4 to 8 weeks are usual. Taking pantoprazole for many months can lower magnesium and vitamin B12 and may increase fracture risk, so long-term use needs a doctor's supervision.
Can I take Pan 40 with alcohol?
There is no direct drug interaction, but alcohol worsens acidity and reflux and will undo the benefit. Keep alcohol to a minimum during treatment.
Is Pan 40 available without prescription in India?
Pantoprazole is a Schedule H medicine, which means it should be sold only against a doctor's prescription. Chemists are required to see a prescription.
Pan 40 vs Pan D – what is the difference?
Pan 40 contains only pantoprazole 40 mg and treats acidity and reflux. Pan D adds domperidone 30 mg, which also helps with nausea, bloating and slow stomach emptying. Your doctor picks based on your symptoms.
Can I take Pan 40 with Dolo 650 or other painkillers?
Yes. In fact doctors often prescribe pantoprazole alongside painkillers like diclofenac or aceclofenac to protect the stomach. There is no interaction with paracetamol.
How long does Pan 40 take to work?
You may feel less heartburn within a day, but it can take 2 to 3 days of regular use for full effect. It is not a quick-relief antacid.
Is Pan 40 safe in pregnancy?
It is used in pregnancy only if your doctor decides it is needed. Tell your doctor if you are pregnant, planning pregnancy or breastfeeding.
Can I stop Pan 40 suddenly?
After a long course, stopping suddenly can cause rebound acidity for a few days. Your doctor may reduce the dose gradually or switch you to an antacid for a short time.
Sources
- NHS – Pantoprazole (19 October 2026)
- MedlinePlus – Pantoprazole (19 October 2026)
- NPPA Pharma Sahi Daam (ceiling prices) (19 October 2026)
- PMBI Jan Aushadhi Product & MRP List (19 October 2026)
Medyzen Editorial Team · Last updated
This page is general information, not medical advice. Do not start, stop or change a medicine without asking a doctor or pharmacist. Terms