Sucralfate 1 g: uses, price & cheaper substitutes
Prescription required (Schedule H)
Common uses: Healing duodenal ulcers (ulcers in the first part of the small intestine); Preventing duodenal ulcers from coming back, at a lower maintenance dose.
Listed MRPs range from ₹5.25 to ₹38.91 per tablet across 6 listings. Use only on a doctor's prescription.
Price comparison
| Brand | Manufacturer | Pack | MRP | ₹ / tablet | As on |
|---|---|---|---|---|---|
| Sucrafil 1gm | Fourrts India Laboratories Pvt Ltd | 10 | ₹52.50 | ₹5.25 | 19 October 2026 |
| Sucramal | A. Menarini India Pvt Ltd | 10 | ₹65.63 | ₹6.56 | 19 October 2026 |
| Pepsigard 1gm | SAF Fermion Ltd | 10 | ₹77.34 | ₹7.73 | 19 October 2026 |
| Ulcekon 1gm | FDC Ltd | 10 | ₹111.56 | ₹11.16 | 19 October 2026 |
| Sucral | Strassenburg Pharmaceuticals.Ltd | 10 | ₹124.00 | ₹12.40 | 19 October 2026 |
| Ulcerfate 1gm | Sun Pharmaceutical Industries Ltd | 6 | ₹233.44 | ₹38.91 | 19 October 2026 |
MRPs as printed/listed on the date shown; actual price may vary.
Uses
- Healing duodenal ulcers (ulcers in the first part of the small intestine).
- Preventing duodenal ulcers from coming back, at a lower maintenance dose.
- Stomach ulcers and gastritis, including those caused by painkillers, when a doctor prescribes it.
- Protecting the stomach lining in people who cannot take acid-blocking tablets.
How to take it
For an active ulcer, take one 1 g tablet four times a day on an empty stomach – one hour before each meal and at bedtime. For preventing recurrence, one tablet twice a day. Swallow with water; the tablet is large, so it can be broken or dispersed in a little water if your doctor allows. Sucralfate works by coating the ulcer, so it must be taken at the same times each day for the full course – ulcers can take 4 to 8 weeks to heal. Keep antacids 30 minutes away and most other medicines 2 hours away, as sucralfate blocks their absorption. See a doctor if you have black stools or vomit blood.
Side effects
Common
- Constipation – the main side effect.
- Dry mouth.
- Nausea or stomach discomfort.
- Bloating.
Serious
Stop and get medical help urgently if you notice any of these.
- Severe allergic reaction – hives, rash, swelling of the face or throat, difficulty breathing.
- Aluminium build-up in people with kidney failure – confusion, bone pain, weakness.
- A hard mass (bezoar) in the stomach in people with poor stomach emptying or on tube feeding – severe pain, vomiting.
Safety information
Alcohol
No direct interaction, but alcohol irritates the stomach and delays ulcer healing. Avoid it during treatment.
Pregnancy
Tell your doctor if you are pregnant or breastfeeding. Very little sucralfate is absorbed, so it is often considered acceptable in pregnancy, but take it only on medical advice.
Kidney problems
Sucralfate contains aluminium, which can build up if your kidneys are weak or you are on dialysis. Tell your doctor about kidney disease; long courses may be avoided.
Liver problems
No special dose change, but tell your doctor about liver disease.
Children
Used in children only on a doctor's prescription; the 1 g tablet is an adult dose.
Missed dose
Take it when you remember unless the next dose is nearly due – then skip it. Do not double the dose.
Interactions
- Antacids (Digene, Gelusil) – take at least 30 minutes before or after sucralfate.
- Quinolone antibiotics (ciprofloxacin, norfloxacin, levofloxacin), tetracyclines – sucralfate blocks their absorption; take them 2 hours before sucralfate.
- Thyroxine (Thyronorm), digoxin, phenytoin, warfarin, ketoconazole – absorption reduced; separate by 2 hours and tell your doctor.
- Famotidine, pantoprazole and other acid blockers – can be used together but tell your doctor; they are usually spaced apart.
Frequently asked questions
Sucral tablet before or after food?
Before food, on an empty stomach – about one hour before each meal and at bedtime. It needs to coat the ulcer before food and acid arrive.
Sucral tablet vs Sucral O or Sucralfate syrup – what is the difference?
Sucral tablets contain sucralfate 1 g. Sucral-O and similar syrups combine sucralfate with oxetacaine, a local anaesthetic, for painful gastritis. Suspensions are easier to swallow and coat the food pipe; tablets suit duodenal ulcers. Your doctor picks the form.
Sucralfate vs pantoprazole – which is better for ulcers?
Pantoprazole reduces acid production and heals ulcers faster, so it is usually first choice. Sucralfate coats and protects the ulcer without changing acid, so it is useful when PPIs are unsuitable or as an add-on. Some doctors prescribe both, spaced apart.
Can I take Sucral with alcohol?
Avoid alcohol while treating an ulcer. It irritates the stomach lining and delays healing, undoing the protective effect.
Why do I get constipation on sucralfate?
Sucralfate contains aluminium, which slows the bowel. Drink plenty of water, eat fibre, and tell your doctor if it is severe; a mild laxative may be added.
Can I take Sucral with my thyroid tablet?
Sucralfate blocks absorption of thyroxine. Take Thyronorm first thing in the morning on an empty stomach and sucralfate at least 2 hours later.
Is sucralfate safe in pregnancy?
Very little is absorbed into the body, so it is often considered acceptable in pregnancy when needed, but take it only after checking with your doctor.
How long does sucralfate take to heal an ulcer?
Pain often improves within a few days, but the ulcer itself takes 4 to 8 weeks to heal. Complete the course even when you feel better.
Sources
- MedlinePlus – Sucralfate (19 October 2026)
- NPPA Pharma Sahi Daam (ceiling prices) (19 October 2026)
- PMBI Jan Aushadhi Product & MRP List (19 October 2026)
Medyzen Editorial Team · Last updated
This page is general information, not medical advice. Do not start, stop or change a medicine without asking a doctor or pharmacist. Terms