Fluticasone propionate 50 mcg per spray: uses, price & cheaper substitutes
Prescription required (Schedule H)
Common uses: Allergic rhinitis – sneezing, runny or blocked nose and itchy nose caused by dust, pollen, pollution or pet dander; Hay fever and seasonal allergies, including the sneezing that flares in spring, during harvest season and in Delhi-NCR smog.
Listed MRPs range from ₹0.75 to ₹53.05 per ml across 7 listings. Use only on a doctor's prescription.
Price comparison
| Brand | Manufacturer | Pack | MRP | ₹ / ml | As on |
|---|---|---|---|---|---|
| Fluticasone Propionate Nasal Spray IP 50 mcgJan Aushadhi | Jan Aushadhi (PMBJP) | 100 ml | ₹75.00 | ₹0.75 | 19 October 2026 |
| Nazomac-F Nasal Spray | Macleods Pharmaceuticals Pvt Ltd | 12 ml | ₹344.83 | ₹28.74 | 19 October 2026 |
| Nezaflo Nasal Spray | Sun Pharmaceutical Industries Ltd | 12 ml | ₹421.88 | ₹35.16 | 19 October 2026 |
| Flutiloc Nasal Spray | Satvik Medisolutions | 10 ml | ₹380.00 | ₹38.00 | 19 October 2026 |
| Fluticone Nasal Spray | Zydus Cadila | 12 ml | ₹546.20 | ₹45.52 | 19 October 2026 |
| Flutiflo Nasal Spray | Lupin Ltd | 10 ml | ₹487.95 | ₹48.80 | 19 October 2026 |
| Flomist Nasal Spray | Cipla Ltd | 10 ml | ₹530.49 | ₹53.05 | 19 October 2026 |
MRPs as printed/listed on the date shown; actual price may vary.
Uses
- Allergic rhinitis – sneezing, runny or blocked nose and itchy nose caused by dust, pollen, pollution or pet dander.
- Hay fever and seasonal allergies, including the sneezing that flares in spring, during harvest season and in Delhi-NCR smog.
- Year-round (perennial) allergic rhinitis from house dust mites and mould, common in monsoon months.
- Non-allergic rhinitis – a constantly running or blocked nose with no allergy cause, when your doctor prescribes it.
- Along with other treatment for sinus inflammation (rhinosinusitis) and nasal polyps, as directed by an ENT doctor.
How to take it
Shake the bottle and, if it is new or has not been used for a few days, pump it into the air until a fine mist appears. Blow your nose gently, close one nostril with a finger, tilt your head slightly forward and put the nozzle into the other nostril. Press the pump while breathing in slowly through the nose, then breathe out through the mouth and repeat on the other side. The usual adult dose is 1 or 2 sprays in each nostril once a day, usually in the morning; your doctor may advise twice a day at first and then reduce to the lowest dose that controls symptoms. It is not a quick-relief spray – it can take a few days to start working and up to 2 weeks for full effect, so use it every day even if you feel no change at first. Wipe the nozzle and replace the cap after each use and do not share the bottle. Do not spray it into the eyes or mouth. Tell your doctor if you feel no better after 7 days, and do not use it continuously for more than a month without a doctor reviewing you.
Side effects
Common
- Dry or sore nose, stinging or burning inside the nose.
- Nosebleeds or blood-streaked mucus.
- Unpleasant taste or smell, dry or sore throat, hoarse voice.
- Headache.
- Sneezing just after spraying.
Serious
Stop and get medical help urgently if you notice any of these.
- Eyesight changes – blurred vision, seeing halos or eye pain; long-term use can raise the risk of glaucoma or cataract. See a doctor.
- Severe or frequent nosebleeds, sores or a whistling sound from the nose (damage to the nasal septum) – stop and see an ENT doctor.
- White patches in the nose, mouth or throat, thick nasal discharge with face pain or fever (possible fungal or bacterial infection).
- Serious allergic reaction – swelling of the face, lips or throat, rash, wheezing or difficulty breathing. Get emergency help.
Safety information
Alcohol
Alcohol does not interact with fluticasone nasal spray. You can drink in moderation while using it.
Pregnancy
Fluticasone nasal spray is considered safe in pregnancy and breastfeeding because very little of the steroid reaches the bloodstream. Still tell your doctor if you are pregnant, planning a pregnancy or breastfeeding so they can confirm it is the right choice.
Kidney problems
No dose change is needed for kidney disease because almost none of the spray is absorbed into the body. Tell your doctor anyway.
Liver problems
Tell your doctor if you have liver disease. Steroid levels in the blood can be a little higher in severe liver disease, especially with high doses used for a long time.
Children
In India fluticasone propionate nasal spray is prescribed for children aged 4 years and above at a lower dose, only under a doctor’s care. Children and teenagers using high doses for a long time may need their height and growth checked.
Missed dose
Use it as soon as you remember, unless your next dose is nearly due – then skip the missed one. Do not use 2 doses together to make up for a forgotten one.
Interactions
- Antifungal tablets such as ketoconazole and itraconazole – can raise fluticasone levels in the body and increase steroid side effects; tell your doctor.
- HIV medicines such as ritonavir and cobicistat – strongly raise fluticasone levels; your doctor may choose a different spray.
- Other steroid medicines – inhaled (budesonide, Seroflo/Foracort inhalers), tablets (prednisolone, Omnacortil) or creams – the total steroid dose adds up and can rarely lower your adrenal gland function.
- Decongestant drops like Otrivin (xylometazoline) – can be used for a few days alongside, but do not use decongestant drops for more than a week.
- Antihistamine tablets such as cetirizine, levocetirizine or fexofenadine – commonly combined and generally safe; your doctor decides whether you need both.
Frequently asked questions
How many times a day should I use Flomist nasal spray?
The usual adult dose is 1 or 2 sprays in each nostril once a day, preferably in the morning. Your doctor may start you on twice a day and then bring it down to the lowest dose that controls your symptoms. Do not use more sprays than prescribed.
How long does Flomist take to work?
Fluticasone is not an instant decongestant. Some people feel better in 1 to 2 days, but it can take up to 2 weeks for the full effect. Use it every day and tell your doctor if you feel no better after 7 days.
Is Flomist a steroid? Is it safe to use every day?
Yes, fluticasone propionate is a corticosteroid, but it acts mostly inside the nose and very little enters the bloodstream. Used at the prescribed dose it is unlikely to cause lasting harm. Long-term daily use should be reviewed by your doctor, especially at high doses.
Can I use Flutiflo nasal spray during pregnancy?
Fluticasone nasal spray is considered safe in pregnancy and while breastfeeding because almost none of the steroid reaches the baby. Still tell your doctor that you are pregnant so they can confirm it is right for you.
Flomist vs Otrivin – what is the difference?
Otrivin contains xylometazoline, a decongestant that opens a blocked nose within minutes but should not be used for more than about a week because the blockage can come back worse. Flomist contains fluticasone, a steroid that reduces the allergy inflammation itself, works over days and is meant for regular use. Many doctors use both briefly at the start, then continue only the steroid spray.
Fluticasone propionate vs fluticasone furoate (Avamys) – are they the same?
They are two related molecules. Fluticasone propionate 50 mcg sprays (Flomist, Flutiflo, Nezaflo) and fluticasone furoate sprays (Avamys) both treat allergic rhinitis. Do not swap one for the other on your own – the dose in micrograms is different. Use the one your doctor prescribed.
Does fluticasone nasal spray cause nosebleeds?
A dry nose, mild stinging and small nosebleeds are among the most common side effects. If this happens, stop the spray for a few days and restart; aim the nozzle towards the outer wall of the nostril, not the middle. See a doctor if nosebleeds are heavy or keep coming back.
Can children use Nezaflo or Flomist nasal spray?
Fluticasone propionate nasal spray is prescribed in India for children from about 4 years of age at a lower dose, only when a doctor advises. Children on high doses for a long time should have their growth checked by the doctor.
Can I take cetirizine or Allegra with fluticasone nasal spray?
Yes, antihistamine tablets such as cetirizine, levocetirizine or fexofenadine (Allegra) are often combined with a steroid nasal spray when symptoms are moderate to severe. There is no interaction between them. Ask your doctor whether you still need both once the spray has started working.
Is Flomist available without a prescription in India?
Fluticasone propionate nasal spray is a Schedule H medicine in India and chemists are supposed to sell it only against a doctor’s prescription, even though 1mg and other sites mark it as Rx. A Jan Aushadhi version is also available at a lower price with a prescription.
Sources
- NHS – Fluticasone nasal spray and drops (19 October 2026)
- MedlinePlus – Fluticasone Nasal Spray (19 October 2026)
- NPPA Pharma Sahi Daam (ceiling prices) (19 October 2026)
- PMBI Jan Aushadhi Product & MRP List (19 October 2026)
Medyzen Editorial Team · Last updated
This page is general information, not medical advice. Do not start, stop or change a medicine without asking a doctor or pharmacist. Terms