Pantoprazole + Levosulpiride 40 mg + 75 mg (SR): uses, price & cheaper substitutes
Prescription required (Schedule H)
Common uses: Acid reflux (GERD) with bloating, fullness and slow stomach emptying; Functional dyspepsia – indigestion, early fullness after meals, nausea and belching without an ulcer.
Listed MRPs range from ₹5.16 to ₹38.77 per capsule across 9 listings. Use only on a doctor's prescription.
Price comparison
| Brand | Manufacturer | Pack | MRP | ₹ / capsule | As on |
|---|---|---|---|---|---|
| Pantoprazole 40mg (Enteric Coated) and Levosulpiride 75mg (Sustained Release) CapsulesJan Aushadhi | Jan Aushadhi (PMBJP) | 10 | ₹51.57 | ₹5.16 | 19 October 2026 |
| Volapride-Plus | Mankind Pharma Ltd | 10 | ₹154.71 | ₹15.47 | 19 October 2026 |
| Pansec-L | Cipla Ltd | 10 | ₹190.86 | ₹19.09 | 19 October 2026 |
| Nupenta LS | Macleods Pharmaceuticals Pvt Ltd | 10 | ₹276.70 | ₹27.67 | 19 October 2026 |
| Pantop LS | Aristo Pharmaceuticals Pvt Ltd | 10 | ₹277.00 | ₹27.70 | 19 October 2026 |
| Pantium-L | Intas Pharmaceuticals Ltd | 10 | ₹284.53 | ₹28.45 | 19 October 2026 |
| Pantocid L | Sun Pharmaceutical Industries Ltd | 10 | ₹298.13 | ₹29.81 | 19 October 2026 |
| Pantodac L | Zydus Cadila | 10 | ₹379.64 | ₹37.96 | 19 October 2026 |
| Protera-L | Lupin Ltd | 10 | ₹387.70 | ₹38.77 | 19 October 2026 |
MRPs as printed/listed on the date shown; actual price may vary.
Uses
- Acid reflux (GERD) with bloating, fullness and slow stomach emptying.
- Functional dyspepsia – indigestion, early fullness after meals, nausea and belching without an ulcer.
- Gastroparesis (slow stomach emptying), for example in diabetes, when a doctor prescribes it.
- Short-term relief of heartburn and nausea where a plain acid-reducer alone has not helped.
How to take it
Take one capsule once a day, about 30 to 60 minutes before breakfast, or as your doctor prescribes. Swallow it whole with water – do not open, crush or chew, because the pantoprazole pellets are coated and the levosulpiride is sustained-release. Pantoprazole reduces stomach acid and levosulpiride speeds up stomach emptying and eases nausea. This combination is meant for short courses, usually 2 to 4 weeks; levosulpiride should not be taken for months because of the risk of movement disorders and raised prolactin. See your doctor if symptoms persist beyond the course, if you have difficulty swallowing, vomiting, black stools or unexplained weight loss.
Side effects
Common
- Headache.
- Diarrhoea or constipation, gas.
- Drowsiness or tiredness.
- Nausea or stomach pain.
- Breast tenderness, milk discharge or period changes (from raised prolactin).
Serious
Stop and get medical help urgently if you notice any of these.
- Uncontrolled movements – tremor, stiffness, restlessness, muscle spasms of the face or neck – stop and see a doctor.
- High fever with stiff muscles, sweating and confusion (neuroleptic malignant syndrome) – emergency.
- Severe watery diarrhoea that does not stop.
- Severe allergic or skin reaction – blistering rash, swelling of the face, difficulty breathing.
Safety information
Alcohol
Avoid alcohol. It worsens acidity and adds to the drowsiness caused by levosulpiride.
Pregnancy
Not recommended in pregnancy or breastfeeding unless your doctor decides it is essential; levosulpiride passes into breast milk.
Kidney problems
Tell your doctor about kidney disease; levosulpiride is cleared by the kidneys and the dose may need lowering.
Liver problems
Use with caution in liver disease; your doctor may choose a lower dose or a different medicine.
Children
Not for children.
Missed dose
Take it as soon as you remember unless the next dose is due soon, then skip it. Do not take two capsules together.
Interactions
- Other medicines that act on the brain – antipsychotics, metoclopramide, antidepressants, sleeping tablets – more drowsiness and movement side effects.
- Parkinson's medicines (levodopa) – levosulpiride works against them; avoid.
- Ketoconazole, itraconazole, iron tablets and some HIV medicines – pantoprazole lowers their absorption.
- Warfarin and clopidogrel – tell your doctor; monitoring may be needed.
- Antacids – take at a different time from the capsule.
Frequently asked questions
What is Pantocid L used for?
Pantocid L contains pantoprazole 40 mg and levosulpiride 75 mg. Pantoprazole reduces stomach acid and levosulpiride speeds up stomach emptying, so it is prescribed for reflux and indigestion with bloating, fullness and nausea.
Pantocid 40 vs Pantocid L vs Pantocid D – what is the difference?
Pantocid 40 is pantoprazole alone for acidity. Pantocid D adds domperidone and Pantocid L adds levosulpiride; both help nausea and slow stomach emptying. Levosulpiride is somewhat stronger but has more side effects on movement and prolactin, so it is kept to short courses.
Pantocid L before or after food?
Before food. Take it 30 to 60 minutes before breakfast so acid is suppressed and the stomach empties better at mealtime.
Can I take Pantocid L daily for a long time?
No. Levosulpiride should not be taken for months because it can cause tremor, stiffness, restlessness and raised prolactin. If you need acid treatment long term, your doctor will usually switch you to pantoprazole alone.
Can I take Pantocid L with alcohol?
Best avoided. Alcohol worsens reflux and increases drowsiness with levosulpiride.
Does Pantocid L cause breast discharge or period problems?
Levosulpiride raises prolactin, which can cause breast tenderness, milky discharge, missed periods or reduced sex drive. Tell your doctor; it settles after stopping.
Is Pantocid L safe in pregnancy?
It is not recommended in pregnancy or breastfeeding unless your doctor decides it is essential. Plain antacids or pantoprazole alone are usually preferred.
Can I take Pantop LS with Dolo 650 or Combiflam?
There is no interaction with paracetamol. Painkillers like ibuprofen or diclofenac can irritate the stomach, and your doctor may actually prescribe pantoprazole alongside them.
Is Pantocid L available without a prescription?
No. Both ingredients are Schedule H in India and levosulpiride in particular needs a doctor's supervision.
Sources
- MedlinePlus – Pantoprazole (19 October 2026)
- NHS – Pantoprazole: side effects (19 October 2026)
- NHS – Metoclopramide (same class of prokinetic as levosulpiride) (19 October 2026)
- NPPA Pharma Sahi Daam (ceiling prices) (19 October 2026)
- PMBI Jan Aushadhi Product & MRP List (19 October 2026)
Medyzen Editorial Team · Last updated
This page is general information, not medical advice. Do not start, stop or change a medicine without asking a doctor or pharmacist. Terms