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Prednisolone 10 mg: uses, price & cheaper substitutes

Prescription required (Schedule H)

Common uses: Asthma attacks and COPD flare-ups; Severe allergic reactions, hives and drug allergies.

Listed MRPs range from ₹0.61 to ₹1.29 per tablet across 6 listings. Use only on a doctor's prescription.

Price comparison

BrandManufacturerPackMRP₹ / tabletAs on
Prednisolone Tablets IP 10 mgJan AushadhiJan Aushadhi (PMBJP)10₹8.44₹0.8419 October 2026
Nucort Forte 10Mankind Pharma Ltd10₹6.06₹0.6119 October 2026
Predone 10Cipla Ltd10₹8.20₹0.8219 October 2026
Emsolone 10Medopharm20₹24.98₹1.2519 October 2026
Wysolone 10Pfizer Ltd15₹19.14₹1.2819 October 2026
Omnacortil 10Macleods Pharmaceuticals Pvt Ltd10₹12.88₹1.2919 October 2026

MRPs as printed/listed on the date shown; actual price may vary.

Uses

  • Asthma attacks and COPD flare-ups.
  • Severe allergic reactions, hives and drug allergies.
  • Rheumatoid arthritis, lupus and other autoimmune diseases.
  • Nephrotic syndrome and inflammatory bowel disease.
  • Skin conditions such as severe eczema, and some blood disorders and cancers under specialist care.

How to take it

Take the tablets once a day with breakfast, as a single dose, unless your doctor has split it. Food protects the stomach, and a morning dose causes less sleeplessness. Dispersible (DT) tablets can be swallowed or dissolved in a little water. Take exactly the number of tablets written – doses vary widely between conditions. Short courses of a few days can be stopped as directed; after more than about 3 weeks, the dose must be reduced gradually. Carry a steroid card or note if you are on long-term treatment, and tell any doctor, dentist or surgeon you take it.

Side effects

Common

  • Increased appetite and weight gain.
  • Indigestion or heartburn.
  • Trouble sleeping and restlessness.
  • Heavy sweating.
  • Mild mood changes.

Serious

Stop and get medical help urgently if you notice any of these.

  • Infections that take hold easily – fever, sore throat, mouth sores; chickenpox or measles exposure needs urgent advice.
  • High blood sugar – extreme thirst, passing urine often.
  • Black stools or vomiting blood (stomach ulcer).
  • Eye changes – blurred vision, eye pain (cataract or glaucoma).
  • Severe mood change, depression, or thoughts of self-harm; bone thinning and fractures with long-term use.

Safety information

Alcohol

Limit alcohol. Both irritate the stomach and the combination raises the risk of ulcers and bleeding.

Pregnancy

Used in pregnancy and breastfeeding when needed, as only a little crosses to the baby. Tell your doctor; long-term use needs specialist supervision.

Kidney problems

Can cause fluid retention and raised blood pressure; tell your doctor about kidney disease.

Liver problems

Tell your doctor about liver disease; dose may need adjusting.

Children

Widely used in children for asthma, nephrotic syndrome and allergies with weight-based doses. Long courses can slow growth, so a paediatrician monitors height.

Missed dose

Take it as soon as you remember that day. If you only remember the next day, skip the missed dose and continue. Never double the dose.

Interactions

  • Painkillers like ibuprofen, diclofenac, aspirin – much higher risk of stomach bleeding; pantoprazole cover is often prescribed.
  • Diabetes medicines and insulin – blood sugar rises; doses may need adjusting.
  • Warfarin – bleeding risk changes; INR needs checks.
  • Phenytoin, carbamazepine, rifampicin – lower prednisolone levels.
  • Ketoconazole, itraconazole, clarithromycin – raise steroid levels.
  • Live vaccines – avoid during high-dose treatment; ask before any vaccination.

Frequently asked questions

When should I take Wysolone 10?

In the morning with breakfast, as a single dose, unless your doctor has told you to split it. This copies the body's natural steroid rhythm and causes less insomnia.

Can I stop Wysolone 10 suddenly?

After a course of a few days, yes, as directed. After 3 weeks or more, stopping suddenly can cause severe tiredness, weakness, body aches and a flare of the illness – the dose must be tapered by your doctor.

Wysolone vs Omnacortil – what is the difference?

Both contain prednisolone and come as dispersible tablets. They work the same; the choice is usually about availability and price.

Can I take Wysolone 10 with alcohol?

Keep it minimal. Both irritate the stomach and the combination raises the risk of ulcers and bleeding.

Does Wysolone increase blood sugar?

Yes. Steroids raise blood sugar, sometimes a lot in people with diabetes. Check sugar more often and tell your doctor so diabetes medicines can be adjusted.

Is Wysolone 10 safe in pregnancy?

Prednisolone is one of the steroids preferred in pregnancy because very little reaches the baby. Use it only on your doctor's advice at the lowest dose that works.

Why was I given Wysolone with Pan 40?

Steroids can cause stomach ulcers, especially with painkillers. Pantoprazole protects the stomach lining during the course.

Can I take Wysolone 10 if I have an infection or TB history?

Steroids suppress immunity and can reactivate TB or worsen infections. Tell your doctor about any fever, cough, TB history or chickenpox exposure before starting.

Is prednisolone 10 available at Jan Aushadhi?

Yes, prednisolone 10 mg is listed under Jan Aushadhi and is NPPA price-controlled. A prescription is needed.

Sources

Medyzen Editorial Team · Last updated

This page is general information, not medical advice. Do not start, stop or change a medicine without asking a doctor or pharmacist. Terms