Human insulin (30/70 premixed) 100 IU/ml: uses, price & cheaper substitutes
Prescription required (Schedule H)
Common uses: Type 2 diabetes that is no longer controlled on tablets alone; Type 1 diabetes, where the body makes no insulin, usually as part of a twice-daily premixed regimen.
Listed MRPs range from ₹54.57 to ₹104.10 per ml across 4 listings. Use only on a doctor's prescription.
Price comparison
| Brand | Manufacturer | Pack | MRP | ₹ / ml | As on |
|---|---|---|---|---|---|
| Human Mixtard 30 (100 IU/ml) | Novo Nordisk India Pvt Ltd | 10 ml | ₹545.71 | ₹54.57 | 19 October 2026 |
| Insugen 30/70 (100 IU/ml) | Biocon | 10 ml | ₹625.90 | ₹62.59 | 19 October 2026 |
| Huminsulin 30/70 (100 IU/ml) | Eli Lilly and Company India Pvt Ltd | 10 ml | ₹651.00 | ₹65.10 | 19 October 2026 |
| Wosulin 30/70 cartridges | Wockhardt Ltd | 15 ml | ₹1561.50 | ₹104.10 | 19 October 2026 |
MRPs as printed/listed on the date shown; actual price may vary.
Uses
- Type 2 diabetes that is no longer controlled on tablets alone.
- Type 1 diabetes, where the body makes no insulin, usually as part of a twice-daily premixed regimen.
- Diabetes in pregnancy (gestational or pre-existing) when diet does not control sugar.
- Temporary sugar control during illness, surgery or steroid treatment.
How to take it
This is a premixed insulin: 30% short-acting (works within 30 minutes) and 70% intermediate-acting (lasts up to 24 hours), so it is usually injected twice a day, 20 to 30 minutes before breakfast and before dinner, at the dose your doctor sets in units. Roll the vial or pen gently between your palms until the liquid is uniformly cloudy – do not shake, and do not use it if there are clumps. Inject under the skin of the abdomen, thigh or upper arm, rotating sites. Use a syringe marked for 100 IU/ml with this strength – mixing up 40 IU/ml and 100 IU/ml syringes causes serious dosing errors. Never skip or delay the meal after injecting. Check your sugar as advised and keep sugar or glucose tablets with you.
Side effects
Common
- Low blood sugar (hypoglycaemia) – sweating, shakiness, hunger, palpitations, confusion.
- Redness, itching or small lumps at the injection site.
- Weight gain.
- Thickened or dented skin where you inject repeatedly in the same spot.
Serious
Stop and get medical help urgently if you notice any of these.
- Severe hypoglycaemia – unconsciousness or fits; family members should know how to give sugar or glucagon and call for help.
- Severe allergic reaction – rash all over the body, breathlessness, swelling.
- Swelling of the hands or feet, or sudden weight gain, especially with pioglitazone or heart disease.
- Low potassium – muscle cramps, weakness, irregular heartbeat.
Safety information
Alcohol
Alcohol lowers blood sugar for many hours and masks the warning signs. If you drink, do so with food, keep it small and check sugar before bed.
Pregnancy
Human insulin is the preferred diabetes treatment in pregnancy and while breastfeeding because it does not cross to the baby. Doses change through pregnancy, so monitor closely with your doctor.
Kidney problems
Insulin is cleared more slowly when the kidneys are weak, so the dose often needs reducing to avoid hypos. Tell your doctor about kidney disease.
Liver problems
Liver disease changes insulin needs and raises the risk of hypos; dose adjustments are needed.
Children
Used in children with type 1 diabetes under a paediatric diabetes team, with doses by weight and meal plan.
Missed dose
If you remember within an hour or so and are eating, take it with the meal. If the meal is long past, do not take the full dose – check your sugar and ask your doctor what to do. Never take two doses together.
Interactions
- Glimepiride, gliclazide and other sulfonylureas – more risk of hypos; doses are usually reduced when insulin starts.
- Beta blockers (metoprolol, atenolol, propranolol) – hide the warning signs of low sugar.
- Steroids (prednisolone, methylprednisolone), thiazides, some HIV medicines – raise sugar; insulin doses go up during the course.
- Pioglitazone – more fluid retention and heart failure risk with insulin.
- Aspirin in high doses, some antidepressants – can lower sugar further.
- Ayurvedic sugar remedies – can cause unpredictable hypos; tell your doctor.
Frequently asked questions
When should I inject Mixtard 30?
About 20 to 30 minutes before breakfast and before dinner, as your doctor has set. You must eat a proper meal after injecting – skipping the meal causes a hypo.
Mixtard 30 vs Mixtard 50 – what is the difference?
The numbers show the share of short-acting insulin. Mixtard 30 is 30% short-acting and 70% intermediate; Mixtard 50 is 50/50 and covers heavier meals. Only your doctor should change the type.
What is the difference between 40 IU/ml and 100 IU/ml insulin?
Both exist in India. The 100 IU/ml vial is 2.5 times more concentrated than the 40 IU/ml vial and must be used with a U-100 syringe (orange cap). Using the wrong syringe gives a very wrong dose – check the label every time.
How do I store Mixtard 30?
Unopened vials and pens go in the fridge door (2 to 8 degrees C), never the freezer. The vial or pen in use can stay at room temperature below 30 degrees C away from sunlight for the period on the leaflet; in Indian summer keep it in a cool pouch.
Can I take Huminsulin 30/70 with alcohol?
Alcohol can cause delayed low sugar, sometimes hours later and during sleep. If you drink, keep it small, eat with it, and check your sugar before bed.
Is Mixtard 30 safe in pregnancy?
Yes. Human insulin is the standard treatment for diabetes in pregnancy, and the doses are adjusted frequently as the pregnancy progresses.
What should I do if I feel shaky and sweaty after my insulin?
That is a hypo. Immediately take 3 to 4 glucose tablets, a spoon of sugar or half a glass of juice, wait 15 minutes and recheck. Then have a snack. Tell your doctor so the dose can be reviewed.
Can I mix Insugen 30/70 with another insulin?
No. Premixed insulins should not be mixed with anything else in the syringe. If you need a different regimen, your doctor will change the prescription.
Why does the insulin look cloudy?
Premixed 30/70 insulin is meant to look uniformly cloudy after gentle rolling because of the intermediate-acting part. Do not use it if it has clumps, strands or particles stuck to the glass.
Is insulin 30/70 available without prescription?
Insulin is a Schedule H medicine. Chemists are required to see a prescription, and dosing must be set by a doctor.
Sources
- MedlinePlus – Human insulin injection (19 October 2026)
- NPPA Pharma Sahi Daam (ceiling prices) (19 October 2026)
- PMBI Jan Aushadhi Product & MRP List (19 October 2026)
Medyzen Editorial Team · Last updated
This page is general information, not medical advice. Do not start, stop or change a medicine without asking a doctor or pharmacist. Terms