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Hydroxychloroquine 200 mg: uses, price & cheaper substitutes

Prescription required (Schedule H)

Common uses: Rheumatoid arthritis – as a disease-modifying drug to reduce joint pain, swelling and damage; Systemic lupus erythematosus (SLE) and lupus of the skin.

Listed MRPs range from ₹3.38 to ₹6.84 per tablet across 8 listings. Use only on a doctor's prescription.

Price comparison

BrandManufacturerPackMRP₹ / tabletAs on
Hydroxychloroquine Tablets IP 200 mgJan AushadhiJan Aushadhi (PMBJP)10₹33.75₹3.3819 October 2026
Hydroquin 200Sun Pharmaceutical Industries Ltd10₹56.47₹5.6519 October 2026
ZY-Q 200Zydus Cadila30₹201.18₹6.7119 October 2026
Hetq 200Hetero Healthcare Limited10₹67.69₹6.7719 October 2026
OxcQ 200Wallace Pharmaceuticals Pvt Ltd10₹67.83₹6.7819 October 2026
Qdmrd 200Alembic Pharmaceuticals Ltd10₹67.93₹6.7919 October 2026
Hqtor 200Torrent Pharmaceuticals Ltd10₹68.29₹6.8319 October 2026
HCQS 200Ipca Laboratories Ltd15₹102.53₹6.8419 October 2026

MRPs as printed/listed on the date shown; actual price may vary.

Uses

  • Rheumatoid arthritis – as a disease-modifying drug to reduce joint pain, swelling and damage.
  • Systemic lupus erythematosus (SLE) and lupus of the skin.
  • Some other autoimmune and sun-triggered skin conditions, under a specialist.
  • Malaria prevention or treatment in areas where the parasite is still sensitive (chloroquine-sensitive).

How to take it

Take it with a meal or a glass of milk to reduce stomach upset, once or twice a day as prescribed, swallowed whole with water. For arthritis and lupus it takes several weeks to months to work, so keep taking it even if you do not notice a change at first; treatment usually continues for years. Your doctor will base the dose on your body weight. Because long-term use can rarely damage the retina, you need an eye examination at the start and then regularly (usually yearly after 5 years, or sooner if you have risk factors).

Side effects

Common

  • Nausea, stomach pain, diarrhoea, loss of appetite.
  • Headache.
  • Itchy skin rash, darkening of skin.
  • Blurred vision at the start (usually settles).
  • Mood changes.

Serious

Stop and get medical help urgently if you notice any of these.

  • Persistent blurred vision, trouble seeing colours, light sensitivity or blind spots – possible retinal damage; stop and see an eye doctor.
  • Irregular heartbeat, fainting.
  • Severe skin reaction with blisters or peeling.
  • Yellow skin or eyes, dark urine; very low blood sugar; muscle weakness.

Safety information

Alcohol

There is no direct interaction, but alcohol adds to liver strain and stomach upset. Keep it moderate.

Pregnancy

Can be continued in pregnancy and breastfeeding for lupus or arthritis when needed – stopping can cause a flare. Your doctor will use the lowest effective dose.

Kidney problems

Used with caution in kidney disease; a lower dose may be needed.

Liver problems

Use with caution in liver disease; liver tests may be checked.

Children

Used in children with juvenile arthritis or lupus under a specialist, with weight-based dosing.

Missed dose

Take it as soon as you remember unless the next dose is nearly due, then skip it. Do not double up.

Interactions

  • Antacids and indigestion remedies – take at least 4 hours apart; they reduce absorption.
  • Medicines that affect heart rhythm – azithromycin, clarithromycin, levofloxacin, amiodarone, some antidepressants and antipsychotics – higher risk of irregular heartbeat.
  • Diabetes medicines (metformin, glimepiride, insulin) – hydroxychloroquine can lower blood sugar further.
  • Digoxin – levels may rise.
  • Epilepsy medicines – may work less well.
  • Methotrexate and other DMARDs – commonly combined under a rheumatologist, with regular blood tests.

Frequently asked questions

HCQS 200 before or after food?

After food or with a glass of milk, to avoid nausea and stomach pain. Take it at the same time each day.

How long does HCQS 200 take to work for arthritis?

Usually 4 to 12 weeks, sometimes longer, because it modifies the disease rather than just easing pain. Keep taking it; your rheumatologist will review progress.

Does HCQS 200 affect the eyes?

Rarely, long-term use can damage the retina. You need an eye check when you start and regular checks afterwards. Report persistent blurring, colour-vision changes or blind spots immediately.

Is HCQS 200 safe in pregnancy?

Yes, it is usually continued in pregnancy and breastfeeding for lupus and arthritis, because a disease flare is riskier than the medicine. Do not stop without talking to your doctor.

Can I take HCQS 200 with alcohol?

There is no specific interaction, but alcohol can worsen stomach upset and liver strain. Keep it moderate.

HCQS 200 vs HCQS 400 – which dose do I need?

The dose is based on body weight, usually not more than 5 mg per kg per day. Your rheumatologist decides; higher doses increase the risk to the eyes.

Can hydroxychloroquine be used to prevent COVID-19 or viral infections?

No. Large trials found no benefit, and it can cause heart rhythm problems. Use it only for the conditions your doctor has prescribed it for.

Can HCQS 200 be taken with antacids?

Keep a gap of at least 4 hours. Antacids reduce the absorption of hydroxychloroquine.

Sources

Medyzen Editorial Team · Last updated

This page is general information, not medical advice. Do not start, stop or change a medicine without asking a doctor or pharmacist. Terms