Gliclazide 80 mg: uses, price & cheaper substitutes
Prescription required (Schedule H)
Common uses: Type 2 diabetes in adults when diet and exercise alone are not enough; Added to metformin when metformin alone does not control blood sugar.
Listed MRPs range from ₹2.25 to ₹11.47 per tablet across 8 listings. Use only on a doctor's prescription.
Price comparison
| Brand | Manufacturer | Pack | MRP | ₹ / tablet | As on |
|---|---|---|---|---|---|
| Gliclazide Tablets IP 80 mgJan Aushadhi | Jan Aushadhi (PMBJP) | 10 | ₹22.50 | ₹2.25 | 19 October 2026 |
| Glizid 80 | Mankind Pharma Ltd | 15 | ₹95.89 | ₹6.39 | 19 October 2026 |
| Dianorm 80 | Micro Labs Ltd | 15 | ₹115.00 | ₹7.67 | 19 October 2026 |
| Glycigon 80 | Aristo Pharmaceuticals Pvt Ltd | 10 | ₹81.04 | ₹8.10 | 19 October 2026 |
| Cyblex 80 | Eris Lifesciences Ltd | 15 | ₹139.68 | ₹9.31 | 19 October 2026 |
| Reclide 80 | Dr Reddy's Laboratories Ltd | 15 | ₹149.52 | ₹9.97 | 19 October 2026 |
| Glycinorm 80 | Ipca Laboratories Ltd | 15 | ₹168.98 | ₹11.27 | 19 October 2026 |
| Diamicron 80 | Servier India Private Limited | 10 | ₹114.75 | ₹11.47 | 19 October 2026 |
MRPs as printed/listed on the date shown; actual price may vary.
Uses
- Type 2 diabetes in adults when diet and exercise alone are not enough.
- Added to metformin when metformin alone does not control blood sugar.
- An alternative when metformin cannot be used.
How to take it
Take it once or twice a day, just before or with a meal – usually with breakfast, and with dinner if a second dose is prescribed. Swallow the tablet whole with water. Gliclazide makes your pancreas release more insulin, so never take it and then skip the meal; this can cause low blood sugar (hypo). Your doctor will start with a low dose and increase it based on your sugar readings. Keep a sugary snack with you, learn the hypo warning signs (shaking, sweating, hunger, confusion), and check your sugar as advised. It is a long-term medicine – do not stop unless your doctor tells you to. Modified-release (MR) tablets are a different strength and are taken once daily; do not swap between types on your own.
Side effects
Common
- Low blood sugar (hypo) – shakiness, sweating, hunger, dizziness, confusion.
- Stomach pain, nausea or diarrhoea.
- Weight gain.
- Headache.
Serious
Stop and get medical help urgently if you notice any of these.
- Severe hypo with fainting or fits – emergency; give sugar if awake and get help.
- Yellow skin or eyes, dark urine (liver problem).
- Easy bruising, persistent sore throat or fever (blood cell problem).
- Serious allergic reaction – rash, swelling of the face or throat, difficulty breathing.
Safety information
Alcohol
Best avoided. Alcohol raises hypo risk and can hide its warning signs; never drink on an empty stomach.
Pregnancy
Not used in pregnancy or breastfeeding; tell your doctor so you can be switched, usually to insulin.
Kidney problems
Use with caution and a lower dose in kidney disease; hypo risk is higher. Not suitable in severe kidney failure.
Liver problems
Not suitable in severe liver disease; caution and lower doses otherwise.
Children
Not for use in children.
Missed dose
Take it with your next meal if you remember soon; if it is nearly time for the next dose, skip it. Never take two doses together, and never take a dose without eating.
Interactions
- Insulin, metformin and other diabetes medicines – higher hypo risk; doses may need adjusting.
- Fluconazole, clarithromycin, co-trimoxazole – raise gliclazide levels and hypo risk.
- Beta blockers (atenolol, metoprolol) – hide the warning signs of a hypo.
- Steroids such as prednisolone and some diuretics – raise blood sugar.
- Painkillers like aspirin, ibuprofen (NSAIDs) and warfarin – can increase gliclazide's effect.
- Rifampicin – lowers its effect.
Frequently asked questions
What is Diamicron 80 used for?
Diamicron 80 contains gliclazide 80 mg, a sulfonylurea. It lowers blood sugar in type 2 diabetes by making the pancreas release more insulin, and is usually taken with meals once or twice daily.
Diamicron 80 vs Diamicron MR 60 – what is the difference?
Both are gliclazide, but the MR (modified-release) tablet releases the medicine slowly and is taken once daily with breakfast; 60 mg MR is roughly equivalent to 80 mg of the standard tablet. Do not swap between them on your own.
Should Glizid 80 be taken before or after food?
Just before or with a meal. Never take gliclazide and then skip the meal – that is the commonest cause of a hypo.
Can I take Diamicron with alcohol?
It is best avoided. Alcohol with gliclazide raises the risk of low blood sugar and can mask its warning signs.
Does gliclazide cause low blood sugar?
Yes, hypos are its main side effect, especially if you skip meals, exercise hard or drink alcohol. Carry glucose or a sugary snack and learn the warning signs.
Does Diamicron cause weight gain?
Sulfonylureas can cause modest weight gain because insulin promotes fat storage. Diet and exercise help; tell your doctor if it is marked.
Can I take Diamicron 80 with metformin?
Yes. Gliclazide and metformin work in different ways and are often prescribed together. Combination tablets are common in India.
Gliclazide vs glimepiride – which is better?
Both are sulfonylureas. Gliclazide is shorter-acting and is often considered to have a lower hypo risk, especially in older people; glimepiride is once daily and widely used in India. Your doctor chooses based on your sugar pattern and kidney function.
Is Glizid 80 safe for kidney patients?
It can be used with caution and a lower dose in mild to moderate kidney disease, but hypo risk is higher. It is not suitable in severe kidney failure.
Sources
- NHS – Gliclazide (19 October 2026)
- NPPA Pharma Sahi Daam (ceiling prices) (19 October 2026)
- PMBI Jan Aushadhi Product & MRP List (19 October 2026)
Medyzen Editorial Team · Last updated
This page is general information, not medical advice. Do not start, stop or change a medicine without asking a doctor or pharmacist. Terms