Levothyroxine 25 mcg: uses, price & cheaper substitutes
Prescription required (Schedule H)
Common uses: Underactive thyroid (hypothyroidism) – replaces the hormone your thyroid is not making enough of; Mild (subclinical) hypothyroidism, where 25 mcg is a common starting or fine-tuning dose.
Listed MRPs range from ₹0.42 to ₹1.55 per tablet across 8 listings. Use only on a doctor's prescription.
Price comparison
| Brand | Manufacturer | Pack | MRP | ₹ / tablet | As on |
|---|---|---|---|---|---|
| Thyroxine Sodium Tablets IP 25mcgJan Aushadhi | Jan Aushadhi (PMBJP) | 100 | ₹42.19 | ₹0.42 | 19 October 2026 |
| Lethyrox 25 | Intas Pharmaceuticals Ltd | 120 | ₹168.96 | ₹1.41 | 19 October 2026 |
| Thyroxinol 25 | Knoll Pharmaceuticals Ltd | 120 | ₹181.00 | ₹1.51 | 19 October 2026 |
| Thyroneed 25 | Mankind Pharma Ltd | 120 | ₹184.57 | ₹1.54 | 19 October 2026 |
| Thyronorm 25 | Abbott | 120 | ₹186.60 | ₹1.55 | 19 October 2026 |
| Eltroxin 25 | Glaxo SmithKline Pharmaceuticals Ltd | 120 | ₹185.79 | ₹1.55 | 19 October 2026 |
| Thyrox 25 | Macleods Pharmaceuticals Pvt Ltd | 120 | ₹186.60 | ₹1.55 | 19 October 2026 |
| Thyroup 25 | Lupin Ltd | 120 | ₹185.80 | ₹1.55 | 19 October 2026 |
MRPs as printed/listed on the date shown; actual price may vary.
Uses
- Underactive thyroid (hypothyroidism) – replaces the hormone your thyroid is not making enough of.
- Mild (subclinical) hypothyroidism, where 25 mcg is a common starting or fine-tuning dose.
- Hypothyroidism in pregnancy, where good control matters for the baby's development.
- After thyroid surgery or radioactive iodine treatment, and to suppress TSH in some thyroid cancers.
How to take it
Take one tablet once a day on an empty stomach, first thing in the morning, 30 to 60 minutes before breakfast, tea or coffee, with a glass of water. Keep a gap of about four hours from iron, calcium, antacids and multivitamins because they stop it being absorbed. Take it at the same time every day and do not switch brands without telling your doctor, as absorption can differ slightly. Your doctor will check your TSH blood test after about six to eight weeks and adjust the dose – 25 mcg is often a starting dose, especially for older people or those with heart disease. Levothyroxine is usually taken for life; never stop it on your own.
Side effects
Common
- Side effects are usually a sign the dose is too high: palpitations, sweating, feeling hot.
- Headache.
- Restlessness, anxiety or trouble sleeping.
- Hair loss in the first months, which usually settles.
Serious
Stop and get medical help urgently if you notice any of these.
- Chest pain, very fast or irregular heartbeat – especially if you have heart disease; see a doctor.
- Signs of a thyroid crisis from too much hormone – high fever, confusion, severe racing heart.
- Severe allergic reaction – swelling of the face or throat, difficulty breathing.
- Long-term over-replacement can thin the bones; regular TSH checks prevent this.
Safety information
Alcohol
Alcohol does not interact directly, but avoid taking the tablet with anything other than water.
Pregnancy
Safe and important in pregnancy – the dose often needs to be increased, so tell your doctor as soon as you know you are pregnant and get TSH checked each trimester. Safe while breastfeeding.
Kidney problems
No dose change for kidney disease.
Liver problems
No dose change usually needed, but tell your doctor about liver disease.
Children
Used in children, including newborns with congenital hypothyroidism, with the dose set by weight under a paediatrician.
Missed dose
Take it as soon as you remember unless the next dose is nearly due – then skip it. Do not take two doses together.
Interactions
- Iron, calcium, antacids, sucralfate and multivitamins – block absorption; keep a gap of about four hours.
- Omeprazole, pantoprazole and other acid reducers can reduce absorption over time.
- Carbamazepine, phenytoin and rifampicin speed up levothyroxine breakdown; the dose may need raising.
- Warfarin – the effect may increase; INR may need checking. Digoxin and beta blockers may need adjusting.
- Soya products, coffee and high-fibre meals close to the dose reduce absorption; biotin supplements can distort thyroid test results.
Frequently asked questions
What is Thyronorm 25 used for?
Thyronorm 25 contains levothyroxine 25 mcg, a synthetic thyroid hormone. It treats an underactive thyroid and is often the starting or fine-tuning dose, especially in older people or those with heart disease.
Why must Thyronorm be taken on an empty stomach?
Food, tea, coffee and milk reduce how much levothyroxine your body absorbs. Taking it first thing in the morning with water, 30 to 60 minutes before breakfast, keeps your dose consistent.
Thyronorm vs Eltroxin – is there a difference?
Both are levothyroxine from different manufacturers and work the same way. Small absorption differences can exist between brands, so stick to one brand and tell your doctor if the chemist substitutes.
Can I take Thyronorm with calcium or iron tablets?
Not at the same time. Iron, calcium and antacids block absorption – keep a gap of about four hours between them and your thyroid tablet.
Is Thyronorm 25 safe in pregnancy?
Yes, and it is essential – untreated hypothyroidism affects the baby's brain development. The dose usually needs increasing in pregnancy, so get TSH checked as soon as you know you are pregnant.
What if I forget my Thyronorm for a day?
Take it as soon as you remember unless it is nearly time for the next dose, in which case skip it. One missed dose will not harm you because the hormone stays in the body for days, but do not double up.
Can I stop Thyronorm once my TSH is normal?
No. Your TSH is normal because of the medicine. Hypothyroidism is usually lifelong and stopping makes symptoms return within weeks. Only your doctor should adjust or stop it.
Does Thyronorm cause hair loss or weight gain?
Some hair shedding can occur in the first months and usually settles. Weight gain is a symptom of under-treatment, not of the medicine – if it continues, ask your doctor to check your TSH.
Is Thyronorm a prescription medicine?
Yes. Levothyroxine is a Schedule H medicine and needs a prescription, plus TSH blood tests to set the right dose.
Sources
- NHS – Levothyroxine (19 October 2026)
- NPPA Pharma Sahi Daam (ceiling prices) (19 October 2026)
- PMBI Jan Aushadhi Product & MRP List (19 October 2026)
Medyzen Editorial Team · Last updated
This page is general information, not medical advice. Do not start, stop or change a medicine without asking a doctor or pharmacist. Terms