Tranexamic acid 500 mg: uses, price & cheaper substitutes
Prescription required (Schedule H)
Common uses: Heavy menstrual bleeding (menorrhagia) – reduces blood loss during periods; Nosebleeds that do not stop, and bleeding after dental extraction in people with bleeding disorders.
Listed MRPs range from ₹7.40 to ₹19.93 per tablet across 9 listings. Use only on a doctor's prescription.
Price comparison
| Brand | Manufacturer | Pack | MRP | ₹ / tablet | As on |
|---|---|---|---|---|---|
| Tranexamic Acid Tablets IP 500 mgJan Aushadhi | Jan Aushadhi (PMBJP) | 10 | ₹74.00 | ₹7.40 | 19 October 2026 |
| Texakind 500 | Mankind Pharma Ltd | 10 | ₹160.03 | ₹16.00 | 19 October 2026 |
| Tranlok 500 | Aristo Pharmaceuticals Pvt Ltd | 10 | ₹163.85 | ₹16.38 | 19 October 2026 |
| Tenacid 500 | Leeford Healthcare Ltd | 10 | ₹180.00 | ₹18.00 | 19 October 2026 |
| Clip 500 | FDC Ltd | 10 | ₹181.07 | ₹18.11 | 19 October 2026 |
| Clostop 500 | Alembic Pharmaceuticals Ltd | 10 | ₹198.00 | ₹19.80 | 19 October 2026 |
| Trenaxa 500 | Macleods Pharmaceuticals Pvt Ltd | 10 | ₹198.03 | ₹19.80 | 19 October 2026 |
| Pause 500 | Emcure Pharmaceuticals Ltd | 10 | ₹199.29 | ₹19.93 | 19 October 2026 |
| Trapic 500 | Sun Pharmaceutical Industries Ltd | 10 | ₹199.29 | ₹19.93 | 19 October 2026 |
MRPs as printed/listed on the date shown; actual price may vary.
Uses
- Heavy menstrual bleeding (menorrhagia) – reduces blood loss during periods.
- Nosebleeds that do not stop, and bleeding after dental extraction in people with bleeding disorders.
- Bleeding after surgery, delivery (postpartum haemorrhage) or injury, usually in hospital.
- Hereditary angioedema, and some doctors use it for melasma (skin pigmentation) off-label.
How to take it
For heavy periods, take the tablets only on the days of heavy bleeding, usually two tablets (1 g) three times a day for up to 4 days, starting when bleeding begins – your doctor may adjust this. Swallow them whole with water, with or without food, and space the doses evenly through the day. For other bleeding, the usual course is up to 7 days. Do not take it every day of the month or for longer than prescribed. It reduces bleeding but does not fix the cause, so heavy periods still need a check for fibroids, anaemia and thyroid problems. Stop and see a doctor at once if you get a painful swollen leg, chest pain, breathlessness or a change in vision.
Side effects
Common
- Nausea, vomiting or diarrhoea – usually mild and dose-related.
- Headache.
- Stomach discomfort.
Serious
Stop and get medical help urgently if you notice any of these.
- Blood clot in a leg (pain, swelling, warmth in the calf) or lung (sudden breathlessness, sharp chest pain, coughing blood) – emergency.
- Changes in colour vision or blurred vision – stop and see a doctor.
- Seizures (rare, mainly with high intravenous doses).
- Severe allergic reaction – swelling of lips or throat, difficulty breathing.
Safety information
Alcohol
No known interaction with alcohol, but alcohol can worsen nausea.
Pregnancy
Used in pregnancy only if a doctor decides it is needed (for example to stop bleeding); it does cross the placenta. Small amounts pass into breast milk and short courses are usually considered acceptable – ask your doctor.
Kidney problems
The dose must be reduced in kidney disease because the drug is removed by the kidneys and can build up. Tell your doctor your creatinine.
Liver problems
No dose change is usually needed; tell your doctor about liver disease.
Children
Used in children for heavy periods or bleeding disorders under a specialist, with weight-based dosing.
Missed dose
Take it as soon as you remember unless the next dose is nearly due; then skip it. Never take two doses together.
Interactions
- Combined oral contraceptive pills (Mala-D, Novelon, Yasmin, etc.) – both increase clot risk; tell your doctor if you are on the pill.
- Hormone replacement therapy and other oestrogens – added clot risk.
- Clotting-factor concentrates and anti-fibrinolytic combinations – only in hospital.
- Blood thinners (warfarin, apixaban, aspirin) – opposing effects; your doctor must know about both.
- Tretinoin (all-trans retinoic acid) for leukaemia – higher clot risk.
Frequently asked questions
What is Pause 500 used for?
Pause contains tranexamic acid 500 mg, which slows the breakdown of blood clots and so reduces bleeding. It is mainly prescribed for heavy periods, and also for nosebleeds, bleeding after tooth extraction, surgery or childbirth.
How should I take Pause 500 for heavy periods?
Only on the heavy days of your period – commonly two tablets three times a day for up to 4 days, starting as soon as bleeding begins. It is not a daily medicine. Your gynaecologist may change the dose depending on how heavy the flow is.
How quickly does Trapic 500 stop bleeding?
It starts working within a few hours and most women notice a clearly lighter flow within the first day of taking it. It reduces blood loss by roughly a third to a half but does not stop the period completely.
Can I take Pause 500 with the contraceptive pill?
Only if your doctor has reviewed you. Both tranexamic acid and oestrogen-containing pills increase the risk of blood clots, so the combination needs a check of your personal risk – age, smoking, family history of clots. Many doctors prefer another approach for heavy periods in pill users.
Does tranexamic acid cause blood clots?
The risk is small but real, which is why it is avoided in people who have had a DVT, pulmonary embolism, stroke or heart attack. Stop and seek urgent help for a painful swollen leg, sudden breathlessness or chest pain.
Is Pause 500 safe in pregnancy?
It is used in pregnancy and after delivery only when a doctor decides it is needed to control bleeding. Do not self-medicate for spotting in pregnancy – bleeding in pregnancy always needs a doctor's assessment.
Pause 500 vs Pause MF – what is the difference?
Pause 500 is plain tranexamic acid. Pause MF adds mefenamic acid, a painkiller, so it treats period pain as well as heavy flow. Choose plain tranexamic acid if you have a stomach ulcer, kidney problems or are already taking another painkiller.
Can tranexamic acid be used for melasma or pigmentation?
Some dermatologists prescribe low-dose oral tranexamic acid off-label for melasma. This needs a proper risk check for clots and should never be self-started; it is a Schedule H medicine.
Will Pause 500 fix my heavy periods permanently?
No. It reduces bleeding during each period but does not treat the cause. If heavy periods continue, you need an evaluation for fibroids, polyps, thyroid disease, bleeding disorders and anaemia, and possibly a hormonal IUD or other long-term treatment.
Sources
- NHS – Tranexamic acid (19 October 2026)
- NPPA Pharma Sahi Daam (ceiling prices) (19 October 2026)
- PMBI Jan Aushadhi Product & MRP List (19 October 2026)
Medyzen Editorial Team · Last updated
This page is general information, not medical advice. Do not start, stop or change a medicine without asking a doctor or pharmacist. Terms