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Apixaban 5 mg: uses, price & cheaper substitutes

Prescription required (Schedule H)

Common uses: Preventing stroke and clots in atrial fibrillation (irregular heartbeat); Treating blood clots in the legs (DVT) and lungs (pulmonary embolism).

Listed MRPs range from ₹3.28 to ₹50.91 per tablet across 9 listings. Use only on a doctor's prescription.

Price comparison

BrandManufacturerPackMRP₹ / tabletAs on
Apixaban Tablets 5mgJan AushadhiJan Aushadhi (PMBJP)10₹32.82₹3.2819 October 2026
Apixapil 5Alkem Laboratories Ltd10₹122.15₹12.2119 October 2026
Elixaban 5Sun Pharmaceutical Industries Ltd10₹179.00₹17.9019 October 2026
Apixator 5Torrent Pharmaceuticals Ltd10₹186.23₹18.6219 October 2026
Pixaflo 5Lupin Ltd10₹196.45₹19.6419 October 2026
Abaxis 5Intas Pharmaceuticals Ltd10₹236.90₹23.6919 October 2026
Apigy 5Cipla Ltd10₹237.08₹23.7119 October 2026
Xapilis 5Abbott10₹237.08₹23.7119 October 2026
Eliquis 5Pfizer Ltd10₹509.06₹50.9119 October 2026

MRPs as printed/listed on the date shown; actual price may vary.

Uses

  • Preventing stroke and clots in atrial fibrillation (irregular heartbeat).
  • Treating blood clots in the legs (DVT) and lungs (pulmonary embolism).
  • Preventing clots from coming back after a DVT or pulmonary embolism.
  • Preventing clots after hip or knee replacement surgery.

How to take it

Take it twice a day, about 12 hours apart, at the same times each day, with or without food. Swallow the tablet with water; if you cannot swallow it whole, it can be crushed and mixed with water or apple juice. The usual dose for atrial fibrillation is 5 mg twice daily, with a lower dose for some older, lighter or kidney-impaired patients; for a fresh clot a higher dose is used for the first week. Unlike warfarin, no INR tests are needed, but you must not miss doses – protection wears off within a day. Do not stop unless your doctor tells you to; stopping suddenly raises stroke risk. Carry your anticoagulant card and tell every doctor and dentist you take it.

Side effects

Common

  • Bleeding more easily – nosebleeds, bleeding gums, bruising, longer bleeding from cuts.
  • Heavier or longer periods.
  • Nausea.
  • Anaemia (tiredness, pale skin).

Serious

Stop and get medical help urgently if you notice any of these.

  • Heavy or internal bleeding – blood in urine or stools, black stools, vomiting blood, coughing blood – go to hospital.
  • Sudden severe headache, confusion, weakness or slurred speech (possible brain bleed) – emergency.
  • Serious allergic reaction – swelling of the face or throat, difficulty breathing.
  • Any head injury or fall – get checked even if you feel fine.

Safety information

Alcohol

Keep alcohol moderate. Heavy drinking raises bleeding risk and can cause falls.

Pregnancy

Not used in pregnancy or breastfeeding. Tell your doctor if you are pregnant or planning pregnancy; a heparin injection is usually used instead.

Kidney problems

The dose may be reduced if your kidneys are weak, and it is avoided in severe kidney failure. Your doctor will check creatinine before and during treatment.

Liver problems

Not suitable in liver disease with bleeding risk; tell your doctor about any liver problem.

Children

Used in children only under a specialist.

Missed dose

Take it as soon as you remember the same day, then continue twice daily as usual. Do not take two doses together to make up.

Interactions

  • Painkillers like aspirin, ibuprofen, diclofenac (NSAIDs) – higher bleeding risk; use paracetamol.
  • Other blood thinners – warfarin, clopidogrel, heparin – only if your doctor plans it.
  • Antifungals ketoconazole and itraconazole, and HIV medicines such as ritonavir – raise apixaban levels; usually avoided.
  • Rifampicin, carbamazepine, phenytoin and St John's wort – lower apixaban levels and reduce protection.
  • SSRI antidepressants (sertraline, escitalopram) – slightly higher bleeding risk.

Frequently asked questions

What is Eliquis 5 used for?

Eliquis 5 is apixaban 5 mg, a newer oral blood thinner. It prevents stroke in atrial fibrillation and treats or prevents clots in the legs and lungs, and after hip or knee replacement.

Eliquis 2.5 vs Eliquis 5 – which one do I need?

5 mg twice daily is the standard dose for atrial fibrillation and for long-term clot treatment. 2.5 mg twice daily is used after joint surgery, for extended prevention after a clot, or when you meet the criteria for dose reduction (older age, low weight, reduced kidney function). Your doctor decides.

Does apixaban need INR blood tests like warfarin?

No. Apixaban has a predictable effect, so routine INR monitoring is not needed. Your doctor will still check your kidney function and haemoglobin from time to time.

Can I take Eliquis 5 with alcohol?

Keep alcohol moderate. Heavy drinking increases bleeding risk and the chance of falls and head injury.

What if I miss a dose of Eliquis?

Take it as soon as you remember the same day and continue your usual twice-daily schedule. Do not double up. Missing doses leaves you unprotected, so set a reminder.

Can I take Ecosprin or painkillers with apixaban?

Low-dose aspirin is combined only when a cardiologist specifically prescribes it. Avoid ibuprofen, diclofenac and other NSAIDs; paracetamol is the safe painkiller.

Do I need to stop Eliquis before surgery or dental work?

Tell the surgeon or dentist in advance. Apixaban is usually paused 24 to 48 hours before procedures with bleeding risk, depending on your kidneys; minor dental work may not need a pause. Never stop it on your own.

Is Apixapil 5 the same as Eliquis?

Yes. Apixapil, Apigy, Elixaban and other Indian brands contain the same apixaban 5 mg as Eliquis. The active molecule and dose are identical; ask your doctor before switching brands.

Is Eliquis safe in pregnancy?

No. Apixaban is not used in pregnancy or while breastfeeding. Tell your doctor if you are pregnant or planning to be; heparin injections are usually used instead.

Sources

Medyzen Editorial Team · Last updated

This page is general information, not medical advice. Do not start, stop or change a medicine without asking a doctor or pharmacist. Terms