Calcitriol + Calcium carbonate + Vitamin K2-7 + Methylcobalamin + L-methylfolate + Magnesium + Zinc 0.25 mcg + 1250 mg (500 mg calcium) + 45 mcg + 1500 mcg + 800 mcg + 50 mg + 7.5 mg: uses, price & cheaper substitutes
Prescription required (Schedule H)
Common uses: Bone loss and osteoporosis when your doctor wants active vitamin D with calcium and other nutrients; Low calcium with low vitamin B12 or folate, as prescribed.
Listed MRPs range from ₹22.00 to ₹30.80 per capsule across 4 listings. Use only on a doctor's prescription.
Price comparison
| Brand | Manufacturer | Pack | MRP | ₹ / capsule | As on |
|---|---|---|---|---|---|
| Geomax D3 Strong | Leeford Healthcare Ltd | 10 | ₹220.00 | ₹22.00 | 19 October 2026 |
| Recalmin D3 Strong | Leeford Healthcare Ltd | 10 | ₹220.00 | ₹22.00 | 19 October 2026 |
| Bio-D3 Strong | Macleods Pharmaceuticals Pvt Ltd | 10 | ₹280.73 | ₹28.07 | 19 October 2026 |
| Calinta Max | Intas Pharmaceuticals Ltd | 10 | ₹307.97 | ₹30.80 | 19 October 2026 |
MRPs as printed/listed on the date shown; actual price may vary.
Uses
- Bone loss and osteoporosis when your doctor wants active vitamin D with calcium and other nutrients.
- Low calcium with low vitamin B12 or folate, as prescribed.
- Bone and nerve support in people with diagnosed deficiencies, on a doctor's advice.
How to take it
Take one softgel a day after a meal, or as your doctor prescribes. Swallow it whole with water. Calcitriol is the active form of vitamin D and can raise blood calcium quickly, so your doctor may check your calcium. Do not add other vitamin D, calcium or B12 products unless your doctor approves. Keep it 1–2 hours apart from other medicines – calcium can reduce the absorption of thyroid tablets, iron and some antibiotics. If you take warfarin, tell your doctor before starting, because this product contains vitamin K. See a doctor if you develop nausea, vomiting, constipation, increased thirst or confusion.
Side effects
Common
- Constipation, belching or upset stomach.
- Loss of appetite or metallic taste.
- Headache.
Serious
Stop and get medical help urgently if you notice any of these.
- High calcium – feeling tired, difficulty thinking clearly, loss of appetite, nausea, vomiting, constipation, increased thirst or urination.
- Irregular heartbeat or confusion – get urgent medical help.
- Allergic reaction – rash, itching, difficulty breathing.
Safety information
Alcohol
No direct interaction; heavy drinking harms bones and the liver, so limit it.
Pregnancy
Use in pregnancy only if your doctor prescribes it. MedlinePlus advises not to breastfeed while taking calcitriol.
Kidney problems
Often prescribed in kidney disease, but only by your doctor with regular blood calcium and phosphate checks. Ask how much fluid you should drink.
Liver problems
Tell your doctor if you have or have had liver disease.
Children
Used in children only under a specialist, with blood tests.
Missed dose
Take it as soon as you remember unless the next dose is nearly due – then skip it. Do not double up.
Interactions
- Warfarin – vitamin K in this product can change how warfarin works; your doctor will need to monitor you.
- Other vitamin D supplements (including 60K capsules and sachets) – risk of high calcium; do not combine without your doctor.
- Calcium supplements – take only as your doctor advises, since calcitriol increases calcium absorption.
- Antacids, laxatives or supplements containing magnesium – tell your doctor before using them.
Frequently asked questions
Bio-D3 Strong capsule uses
Bio-D3 Strong combines calcitriol, calcium carbonate, vitamin K2-7, methylcobalamin, L-methylfolate, magnesium and zinc. Doctors prescribe it for bone loss and low calcium, often with low B12 or folate.
Bio-D3 Strong before or after food?
After a meal is usual, because calcium carbonate is absorbed better with food.
Can I take Bio-D3 Strong with warfarin?
Tell your doctor first. This product contains vitamin K, which affects how warfarin works.
Bio-D3 Strong side effects
Constipation, belching and upset stomach are common. Nausea, vomiting, thirst, confusion or passing urine often may mean high calcium.
Can I take Bio-D3 Strong with vitamin D3 60K?
Not without your doctor, because calcitriol plus extra vitamin D raises the risk of high calcium.
Is Bio-D3 Strong a prescription medicine?
Yes, because it contains calcitriol. Take it only as your doctor prescribes.
Bio-D3 Strong vs GEMcal
Both contain calcitriol, calcium and zinc. Bio-D3 Strong also has vitamin K2-7, methylcobalamin, L-methylfolate and magnesium. Your doctor chooses based on your needs.
How long should I take Bio-D3 Strong?
For the period your doctor prescribes, with periodic blood tests.
Sources
- MedlinePlus – Calcitriol (19 October 2026)
- MedlinePlus – Calcium carbonate (19 October 2026)
- NHS – Vitamin K (19 October 2026)
- MedlinePlus – Warfarin (interactions with supplements) (19 October 2026)
- NHS – B vitamins and folic acid (19 October 2026)
- NPPA Pharma Sahi Daam (ceiling prices) (19 October 2026)
- PMBI Jan Aushadhi Product & MRP List (19 October 2026)
Medyzen Editorial Team · Last updated
This page is general information, not medical advice. Do not start, stop or change a medicine without asking a doctor or pharmacist. Terms