Cholecalciferol (Vitamin D3) 60,000 IU per 5 ml bottle: uses, price & cheaper substitutes
Common uses: Treating vitamin D deficiency confirmed by a blood test, as a weekly or monthly dose; Bone pain, muscle weakness and tiredness caused by low vitamin D.
Listed MRPs range from ₹23.44 to ₹118.93 per ml across 5 listings.
Price comparison
| Brand | Manufacturer | Pack | MRP | ₹ / ml | As on |
|---|---|---|---|---|---|
| Vitamin D3 Oral Solution 60000 IUJan Aushadhi | Jan Aushadhi (PMBJP) | 1 ml | ₹23.44 | ₹23.44 | 19 October 2026 |
| The Old Natural Vitamin D3 60K Nano Shots | Npure Life Science Pvt Ltd | 4 ml | ₹299.00 | ₹74.75 | 19 October 2026 |
| UNS D3 60K Oral Solution | Universal NutriScience | 4 ml | ₹449.00 | ₹112.25 | 19 October 2026 |
| Depura 60K Oral Solution | Sanofi Consumer Healthcare India Limited | 1 ml | ₹116.67 | ₹116.67 | 19 October 2026 |
| Arachitol Nano 60K | Abbott India Limited | 4 ml | ₹475.72 | ₹118.93 | 19 October 2026 |
MRPs as printed/listed on the date shown; actual price may vary.
Uses
- Treating vitamin D deficiency confirmed by a blood test, as a weekly or monthly dose.
- Bone pain, muscle weakness and tiredness caused by low vitamin D.
- Monthly maintenance after deficiency is corrected, as your doctor advises.
How to take it
Drink the full 5 ml bottle directly, or mix it with a little milk or juice, preferably with or after a meal. Take it only at the interval your doctor sets – commonly once a week for several weeks to correct deficiency, then once a month. Never take it daily: one bottle is fifteen times the 4,000 IU daily upper limit for adults. Do not combine it with other vitamin D products unless your doctor has checked the total. See a doctor if you get vomiting, constipation, extreme thirst or confusion.
Side effects
Common
- Usually none at the correct dose.
- Nausea, loss of appetite or constipation.
- Headache or a metallic taste.
Serious
Stop and get medical help urgently if you notice any of these.
- High calcium from too much vitamin D – vomiting, constipation, excessive thirst, passing urine often, confusion, weakness.
- Kidney stones – sharp pain in the side or back.
- Allergic reaction – rash, swelling, difficulty breathing.
Safety information
Alcohol
No direct interaction. Heavy drinking harms bone health, so limit it.
Pregnancy
High-dose vitamin D is used in pregnancy only for confirmed deficiency under a doctor's care; the usual advice is 400 IU a day.
Kidney problems
Not suitable with kidney failure, kidney stones or high calcium without specialist advice.
Liver problems
Tell your doctor if you have liver disease.
Children
Give to children only on a paediatrician's prescription.
Missed dose
Take the missed bottle when you remember unless the next is nearly due – then skip it. Never take two together.
Interactions
- Other vitamin D, calcium or calcitriol products and multivitamins – check the total so you do not take too much.
- Thiazide water pills (hydrochlorothiazide, indapamide) – can raise blood calcium together with vitamin D.
- Epilepsy medicines (phenytoin, carbamazepine, phenobarbital), steroids such as prednisolone, and cholestyramine or liquid paraffin – can reduce vitamin D's effect or absorption.
- Digoxin – high calcium can cause heart rhythm problems.
Frequently asked questions
Depura 60000 uses
Depura 60K contains vitamin D3 60,000 IU in a 5 ml bottle. It is used to treat vitamin D deficiency and for maintenance as a weekly or monthly dose prescribed by a doctor.
How to take Depura 60K?
Drink the whole 5 ml bottle directly or mixed with a little milk or juice, ideally with or after a meal.
How often should I take Depura 60K?
Only as your doctor sets – commonly once a week for several weeks, then once a month. Never daily.
Arachitol Nano vs Depura – any difference?
Both contain vitamin D3 60,000 IU per 5 ml. Follow the same schedule your doctor gives.
Vitamin D3 oral solution vs capsule vs sachet
All give 60,000 IU. Choose the form you find easiest; the dosing schedule is what matters.
Can I take Depura 60K every week for months?
Only as long as your doctor advises. A blood test may be repeated to decide when to switch to monthly maintenance or stop.
Signs of vitamin D toxicity
Nausea, vomiting, constipation, extreme thirst, passing urine often, weakness and confusion – stop and see a doctor.
Is Depura 60K safe in pregnancy?
Only for confirmed deficiency under a doctor's care. Routine advice in pregnancy is 400 IU a day.
Sources
- NHS – Vitamin D (19 October 2026)
- NHS – Colecalciferol: how and when to take it (19 October 2026)
- MedlinePlus – Cholecalciferol (vitamin D3) (19 October 2026)
- NHS – Colecalciferol: taking it with other medicines (19 October 2026)
- NPPA Pharma Sahi Daam (ceiling prices) (19 October 2026)
- PMBI Jan Aushadhi Product & MRP List (19 October 2026)
Medyzen Editorial Team · Last updated
This page is general information, not medical advice. Do not start, stop or change a medicine without asking a doctor or pharmacist. Terms